PMID: 9540762Apr 16, 1998Paper

Low-grade MALT lymphoma involving multiple mucosal sites and bone marrow

Annals of Hematology
G GraziadeiLuca Baldini

Abstract

Mucosa-associated lymphoid tissue (MALT) lymphomas are indolent neoplasms which tend to remain localized for a long time before spreading. We describe here the case of a 36-year-old woman with a low-grade MALT lymphoma involving the lung, stomach, lingual tonsil, and bone marrow at the time of diagnosis. The clonal origin of the pulmonary and bone marrow neoplastic infiltrates was assessed by means of gene rearrangement analysis. All of the involved sites were infiltrated by centrocyte- and monocytoid-like cells expressing the B-cell-associated antigens CD19 and CD20 and showed IgM lambda chain restriction; no CD5, CD10, or CD43 expression was detectable. As the patient had a history of recurrent bronchitis, and computed tomography performed 3 years before the lymphoma diagnosis had already revealed a lesion of the left lung, we conclude that the present case probably represents a pulmonary low-grade MALT lymphoma characterized by an early and unusual involvement of different mucosal sites and bone marrow.

Citations

Mar 16, 2007·Annals of Hematology·Aikaterini MasgalaEleftherios Anevlavis
Feb 22, 2012·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Olga TsachouridouKonstantinos Markou
Apr 1, 2013·Clinical Journal of Gastroenterology·Masahiko OhtakaNobuyuki Enomoto
Jun 17, 2010·American Journal of Clinical Pathology·Sergej KonoplevC Cameron Yin
Jan 13, 2009·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Natsuo TomitaAkinori Takada
Sep 9, 2006·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Mirna D FaresGhassan W Jamaleddine
Jan 18, 2011·Annals of Diagnostic Pathology·Jennifer Chapman-FredricksOffiong Ikpatt
Mar 18, 2008·Journal of the American Academy of Dermatology·Anokhi JambusariaClifford Perlis
Sep 10, 2016·Journal of Community Hospital Internal Medicine Perspectives·Bikram ShresthaAlison Huffstetler
Sep 30, 2016·Archives of Pathology & Laboratory Medicine·Charles M Harmon, Lauren B Smith
Jun 14, 2006·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Markus RadererAndreas Chott
Jul 13, 2002·Expert Review of Anticancer Therapy·M Raderer, P G Isaacson
Sep 11, 2014·World Journal of Gastroenterology : WJG·Lynette LuriaLing Zhang
Feb 11, 2009·The Oncologist·Marina P SiakantarisMaria K Angelopoulou
Nov 24, 1999·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·P L ZinzaniS Tura
May 4, 2005·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Markus RadererAndreas Chott

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.