Low-grade osteosarcoma arising from cemento-ossifying fibroma: a case report

Journal of the Korean Association of Oral and Maxillofacial Surgeons
Yong Bin LeeHyung Jun Kim

Abstract

Cemento-ossifying fibromas are benign tumors, and, although cases of an aggressive type have been reported, no cases of cemento-ossifying fibroma transforming into osteosarcoma have been documented previously. Low-grade osteosarcoma is a rare type of primary bone tumor, representing 1%-2% of all osteosarcomas. A 45-year-old female patient was diagnosed with cemento-ossifying fibroma, treated with mass excision several times over a period of two years and eight months, and followed up. After biopsy gathered because of signs of recurrence, she was diagnosed with low-grade osteosarcoma. The patient underwent wide excision, segmental mandibulectomy, and reconstruction with fibula free flap. The aim of this report is to raise awareness of the possibility that cemento-ossifying fibroma can transform into osteosarcoma and of the consequent necessity for careful diagnosis and treatment planning.

References

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Citations

Nov 17, 2017·Journal of the Korean Association of Oral and Maxillofacial Surgeons·Hye-In JeongHyung Jun Kim
May 8, 2019·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Vivian P WagnerPablo A Vargas
Sep 30, 2019·Clinical Case Reports·Priya MamachanPriyanka Kant

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Methods Mentioned

BETA
biopsy

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