PMID: 15249861Jul 14, 2004Paper

Low-grade trichoblastic carcinosarcoma of the skin

The American Journal of Dermatopathology
Dmitry V KazakovMichal Michal

Abstract

We present an unusual case of cutaneous carcinosarcoma with the epithelial component closely resembling nodular basal cell carcinoma, and the mesenchymal component composed of cells constituting extended follicular papillae. A solitary tumor was excised in an 80-year-old man. Histologic sections revealed an ulcerated, asymmetric, poorly circumscribed neoplasm composed of epithelial cells arranged in lobules with peripheral palisading or in a cribriform pattern. The epithelial cells were darkly basophilic with scant cytoplasm and round or oval nuclei with an indistinct chromatin pattern and nucleoli. Nuclei crowding and mitotic figures were observed. Some lobules contained melanin. There were no shadow cells, sebaceous or apocrine glandular differentiation. Each epithelial nodule was surrounded by multiple rows of cells with pale vesicular nuclei and scant cytoplasm. Smaller epithelial aggregations were encircled by these cells concentrically; in larger ones these cells were aligned across a broad front resembling so-called "continuous papillae". Additionally, numerous small follicular germ-like structures associated with papillae were seen. The cells composing "continuous papillae" showed nuclear pleomorphism, numerous mitotic ...Continue Reading

References

Mar 1, 1977·Oral Surgery, Oral Medicine, and Oral Pathology·R M Howell, E J Burkes
Aug 1, 1990·The American Journal of Dermatopathology·P H McKeeH Pambakian
Feb 1, 1988·Journal of Cutaneous Pathology·J A TschenM H McGavran
Oct 1, 1985·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·M AltiniB B Berezowski
Jan 1, 1984·Virchows Archiv. A, Pathological Anatomy and Histopathology·Y TakedaA Suzuki
Oct 1, 1983·Journal of Cutaneous Pathology·T J HarristM C Mihm
Jun 1, 1981·Journal of Cutaneous Pathology·S C QuayM C Mihm
Apr 1, 1995·Histopathology·E J LeenC E Keen
Jun 1, 1993·Journal of Cutaneous Pathology·S IzakiM Inazu
Dec 1, 1996·The American Journal of Dermatopathology·W BiernatL Woźniak
Sep 1, 1999·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·T J Brown, J A Tschen

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Citations

Feb 8, 2007·The American Journal of Dermatopathology·Renato RossoGiovanni Borroni
Sep 27, 2006·The American Journal of Surgical Pathology·M E Mc MenaminE Calonje
Jan 24, 2008·The American Journal of Dermatopathology·Dmitry V KazakovEduardo Calonje
Aug 17, 2010·The American Journal of Dermatopathology·Dmitry V KazakovMichal Michal
Aug 16, 2014·Der Pathologe·T Mentzel, A Rütten
Aug 13, 2015·Journal of Cutaneous Pathology·Sui Wing Winney Chu, Asok Biswas
Apr 17, 2008·International Journal of Dermatology·Dimitrije BrasanacNada Tomanovic
Aug 23, 2006·Journal of Veterinary Medicine. A, Physiology, Pathology, Clinical Medicine·M Sharif, M Reinacher
Nov 23, 2006·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Jonathan Syme-GrantAlan T Evans
Oct 13, 2016·Journal of Cutaneous Pathology·Joshua J ClarkDavid A Wada
Apr 8, 2017·Annales de chirurgie plastique et esthétique·M ThomasC Dissaux
Jan 8, 2019·Archives of Craniofacial Surgery·Joon Seok LeeKang Young Choi
Jan 15, 2019·Archives of Pathology & Laboratory Medicine·Edward H FultonJerad M Gardner
Jun 23, 2018·The American Journal of Dermatopathology·Ilona OkhremchukJean-Jacques Morand
Feb 11, 2014·Advances in Anatomic Pathology·Thomas Brenn
Apr 9, 2013·The American Journal of Dermatopathology·Ksenya V ShelekhovaDmitry V Kazakov
Apr 5, 2014·The American Journal of Dermatopathology·Nathan T HarveyBenjamin A Wood
Nov 16, 2019·Journal of Cutaneous Pathology·Caroline I M UnderwoodRami N Al-Rohil

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