Low hemoglobin level is associated with the development of delirium after hepatectomy for hepatocellular carcinoma patients

PloS One
Yao-Li ChenPing-Yi Lin

Abstract

Hepatocellular carcinoma (HCC) is one of the most common malignant tumors worldwide and liver resection is the only potential curative treatment option for those patients. Postoperative complications specific to elderly surgical patients such as delirium will be increasingly relevant in the coming decades. Herein, we aimed to investigate the risk factors for postoperative delirium in patients who have received hepatectomy for HCC. This is a single medical center observational study and the study subjects comprised 401 individuals who underwent liver resection for hepatocellular carcinoma during January 2009 to October 2013. Multivariate analysis was used to examine whether preoperative, intra-operative, or postoperative variables were associated with the development of delirium. Of the 401 patients who underwent hepatectomy, 34 developed postoperative delirium (8.4%). In the majority of those patients, symptoms and signs of the syndrome occurred on postoperative day 2 and the mean duration of symptoms was 3.61 ± 3.71 days. Multivariate analysis revealed that advanced age (>71 years) [odds ratio (OR) = 1.133, 95% confidence interval (CI): 1.071-1.200, p<0.001], prolonged operative time (>190 minutes) (OR = 1.009, 95% CI: 1.000-1...Continue Reading

References

Jan 1, 1991·Acta Psychiatrica Scandinavica. Supplementum·W E MüllerC M Gelbmann
Jan 1, 1991·Psychosomatics·L R Dickson
Dec 15, 1990·Annals of Internal Medicine·S K InouyeR I Horwitz
Nov 1, 1994·British Journal of Anaesthesia·S T O'Keeffe, A Ní Chonchubhair
Jan 12, 1994·JAMA : the Journal of the American Medical Association·E R MarcantonioR Poss
Jan 30, 2002·General Hospital Psychiatry·Frank SchneiderWilhelm Sandmann
Mar 1, 2002·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Peter FerenciAndres T Blei
Dec 2, 2004·World Journal of Surgery·Yasuko YoshimuraHiroaki Kinoshita
Mar 1, 2005·The Annals of Thoracic Surgery·Bedrettin YildizeliMustafa Yüksel
May 13, 2005·Journal of Intensive Care Medicine·Ronald DeBellisMichael Malloy
Mar 7, 2006·The Spine Journal : Official Journal of the North American Spine Society·Yoshiharu KawaguchiTomoatsu Kimura
Mar 17, 2006·The New England Journal of Medicine·Sharon K Inouye
Jun 9, 2006·The New England Journal of Medicine·Enrique Anton, Juan Marti
Oct 14, 2006·Journal of the American Geriatrics Society·Monidipa Dasgupta, Andrea C Dumbrell
Aug 9, 2008·Clinical Interventions in Aging·Thomas N Robinson, Ben Eiseman
Dec 25, 2008·Annals of Surgery·Thomas N RobinsonMarc Moss
Feb 13, 2010·Spine·Jin Kyu Lee, Ye-Soo Park
Feb 24, 2010·Surgical Endoscopy·Mitsuyoshi TeiMasaki Mori
Jul 26, 2011·European Journal of Anaesthesiology·Luzius A Steiner
Sep 14, 2011·European Journal of Anaesthesiology·Luzius A Steiner
Jun 16, 2012·Annals of Surgical Oncology·Mari TakeuchiMasaru Mimura

❮ Previous
Next ❯

Citations

Feb 12, 2017·European Journal of Anaesthesiology·César AldecoaClaudia D Spies
Feb 28, 2016·The Journal of International Medical Research·Yong GuoWei Jiang
Dec 30, 2017·BMC Geriatrics·Gizat M KassieElizabeth E Roughead
Jun 14, 2017·World Journal of Surgery·Sung Ae ParkKeizo Dono
Apr 4, 2019·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Yoshito TomimaruKeizo Dono
Sep 23, 2021·Scientific Reports·Mattia SieberDominique Bettex

❮ Previous
Next ❯

Methods Mentioned

BETA
sedation

Software Mentioned

SPSS

Related Concepts

Related Feeds

Attention Disorders

Attention is involved in all cognitive activities, and attention disorders are reported in patients with various neurological diseases. Here are the latest discoveries pertaining to attention disorders.