Low-intensity red and infrared lasers affect mRNA expression of DNA nucleotide excision repair in skin and muscle tissue

Lasers in Medical Science
Luiz Philippe S SergioA S Fonseca

Abstract

Lasers emit light beams with specific characteristics, in which wavelength, frequency, power, fluence, and emission mode properties determine the photophysical, photochemical, and photobiological responses. Low-intensity lasers could induce free radical generation in biological tissues and cause alterations in macromolecules, such as DNA. Thus, the aim of this work was to evaluate excision repair cross-complementing group 1 (ERCC1) and excision repair cross-complementing group 2 (ERCC2) messenger RNA (mRNA) expression in biological tissues exposed to low-intensity lasers. Wistar rat (n = 28, 4 for each group) skin and muscle were exposed to low-intensity red (660 nm) and near-infrared (880 nm) lasers at different fluences (25, 50, and 100 J/cm(2)), and samples of these tissues were withdrawn for RNA extraction, cDNA synthesis, and gene expression evaluation by quantitative polymerase chain reaction. Laser exposure was in continuous wave and power of 100 mW. Data show that ERCC1 and ERCC2 mRNA expressions decrease in skin (p < 0.001) exposed to near-infrared laser, but increase in muscle tissue (p < 0.001). ERCC1 mRNA expression does not alter (p > 0.05), but ERCC2 mRNA expression decreases in skin (p < 0.001) and increases in m...Continue Reading

References

Dec 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·I MellonP C Hanawalt
Apr 24, 1999·Biochimie·C Petit, A Sancar
Jun 12, 1999·Journal of Photochemistry and Photobiology. B, Biology·T Karu
Feb 26, 2000·Carcinogenesis·L J Marnett
Feb 16, 2002·Methods : a Companion to Methods in Enzymology·K J Livak, T D Schmittgen
Mar 20, 2002·Nature Reviews. Cancer·E C Friedberg
Mar 22, 2003·Current Opinion in Cell Biology·James R MitchellLaura J Niedernhofer
Nov 26, 2003·Mutation Research·Geir SlupphaugHans E Krokan
Jan 17, 2004·Biochimie·Renata M A CostaCarlos F M Menck
Jul 29, 2004·DNA Repair·Ari Barzilai, Ken-Ichi Yamamoto
Dec 14, 2004·Advances in Protein Chemistry·Aziz Sancar, Joyce T Reardon
Mar 17, 2005·Physiological Genomics·Robert D BarberBrian J Clark
Nov 28, 2006·DNA Repair·Arne Klungland, Svein Bjelland
Mar 16, 2007·PLoS Biology·Olivier MaillardHanspeter Naegeli
May 6, 2008·Molecular Cancer·Dominique Bernard-GallonYves-Jean Bignon
Dec 10, 2009·Photomedicine and Laser Surgery·Philip V PeplowG David Baxter
May 17, 2011·Food Microbiology·Florence PostollecDanièle Sohier
Jul 7, 2012·Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology·Roberta da Silva MarcianoAdenilson de Souza da Fonseca
Sep 4, 2012·Lasers in Medical Science·Adenilson de Souza da FonsecaFlavia de Paoli
Feb 19, 2013·Journal of Photochemistry and Photobiology. B, Biology·Natalia Camargo RodriguesAna Claudia Muniz Renno
Mar 14, 2013·Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology·Luiz Philippe da Silva SergioAdenilson de Souza da Fonseca
Mar 7, 2014·Lasers in Medical Science·Mario MigliarioFilippo Renò
Apr 20, 2014·Evidence-based Complementary and Alternative Medicine : ECAM·Kathrin H BeckmannSven Schröder
Jun 16, 2014·Lasers in Medical Science·Eduardo Tavares Lima TrajanoAdenilson de Souza da Fonseca
Jun 24, 2014·Nature Reviews. Molecular Cell Biology·Jurgen A MarteijnJan H J Hoeijmakers
Nov 6, 2014·Brazilian Journal of Physical Therapy·Natalia C RodriguesAna C M Renno
Dec 11, 2014·World Journal of Clinical Oncology·Clarice PatronoRenata Cozzi

❮ Previous
Next ❯

Citations

Feb 6, 2019·Lasers in Medical Science·Pierre Augusto Victor da SilvaFlávia de Paoli
Apr 27, 2018·Lasers in Medical Science·Larissa Alexsandra da Silva Neto TrajanoAdenilson de Souza da Fonseca
Jun 3, 2020·Lasers in Medical Science·Luan Viana FariaFlávia de Paoli
Oct 10, 2018·Lasers in Medical Science·Luiz Philippe da Silva SergioAdenilson de Souza da Fonseca
Apr 12, 2018··Adam Mester, Adam Mester

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Lasers in Medical Science
Eduardo Tavares Lima TrajanoAdenilson de Souza da Fonseca
Lasers in Surgery and Medicine
Luiz Philippe da Silva SergioAdenilson de Souza da Fonseca
Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas
L L BarbozaA S Fonseca
Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology
Lawrence C Panasci
© 2022 Meta ULC. All rights reserved