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Low levels of mannose-binding lectin confers protection against tuberculosis in Turkish children

European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology

Jul 10, 2008

Hese CosarCihangir Ozkinay

Abstract

Mannose-binding lectin (MBL) plays an important role in innate immunity mediating phagocytosis and activating the MBL complement pathway. Few studies, conducted in adult populations, have shown that genetically determined low MBL levels may confer partial protection against tuberculosis...read more

Mentioned in this Paper

Complement Pathway
Mannose Binding Lectin
Tuberculosis
MBL2 protein, human
Codon Genus
Codon (Nucleotide Sequence)
Disease Susceptibility
Nested Case-Control Studies
Genetic Equilibrium
MBL2 gene
Paper Details
References
  • References23
  • Citations15
123
  • References23
  • Citations15
12

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Low levels of mannose-binding lectin confers protection against tuberculosis in Turkish children

European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology

Jul 10, 2008

Hese CosarCihangir Ozkinay

PMID: 18612667

DOI: 10.1007/s10096-008-0573-8

Abstract

Mannose-binding lectin (MBL) plays an important role in innate immunity mediating phagocytosis and activating the MBL complement pathway. Few studies, conducted in adult populations, have shown that genetically determined low MBL levels may confer partial protection against tuberculosis...read more

Mentioned in this Paper

Complement Pathway
Mannose Binding Lectin
Tuberculosis
MBL2 protein, human
Codon Genus
Codon (Nucleotide Sequence)
Disease Susceptibility
Nested Case-Control Studies
Genetic Equilibrium
MBL2 gene

Similar Papers Found In These Feeds

Complement Pathway: Mannose-Binding Lectin

The Mannose-Binding Lectin Complement Pathway is activated when mannose-binding lectin binds to mannose found on the surface of pathogens. Subsequent complement activation is similar to the classical complement pathway, but without the need for antigen-antibody complexes. Discover the latest research here.

Structure and Function of DNA

The double helix structure of DNA is important for its biological function. Discover the latest research on the Structure and Function of DNA here.

Related Papers

Paper Details
References
  • References23
  • Citations15
123
  • References23
  • Citations15
12
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