Apr 17, 2015

Low levels of transposable element activity in Drosophila mauritiana: causes and consequences

BioRxiv : the Preprint Server for Biology
Robert Kofler, Christian Schlötterer

Abstract

Transposable elements (TEs) are major drivers of genomic and phenotypic evolution, yet many questions about their biology remain poorly understood. Here, we compare TE abundance between populations of the two sister species D. mauritiana und D. simulans and relate it to the more distantly related D. melanogaster . The low population frequency of most TE insertions in D. melanogaster and D. simulans has been a key feature of several models of TE evolution. In D. mauritiana , however, the majority of TE insertions are fixed (66%). We attribute this to a lower transposition activity of up to 47 TE families in D. mauritiana , rather than stronger purifying selection. Only three families, including the extensively studied Mariner, may have a higher activity in D. mauritiana . This remarkable difference in TE activity between two recently diverged Drosophila species (≈ 250,000 years), also supports the hypothesis that TE copy numbers in Drosophila may not reflect a stable equilibrium where the rate of TE gains equals the rate of TE losses by negative selection. We propose that the transposition rate heterogeneity results from the contrasting ecology of the two species: the extent of vertical extinction of TE families and horizontal a...Continue Reading

  • References
  • Citations

References

  • We're still populating references for this paper, please check back later.
  • References
  • Citations

Citations

  • This paper may not have been cited yet.

Mentioned in this Paper

Drosophila mauritiana
Genome
Transposition of Intestine (Disorder)
Mauritiana
Genomic Stability
Drosophila simulans
Drosophila
Diplopterygium simulans
Dombeya mauritiana
Cellular Transposition

Related Feeds

BioRxiv & MedRxiv Preprints

BioRxiv and MedRxiv are the preprint servers for biology and health sciences respectively, operated by Cold Spring Harbor Laboratory. Here are the latest preprint articles (which are not peer-reviewed) from BioRxiv and MedRxiv.