Low-pressure laparoscopy may ameliorate intracranial hypertension and renal hypoperfusion

Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a
Danny RosinStephen M Cohn

Abstract

Increased abdominal pressure is associated with elevations in the intracranial pressure (ICP) and impaired renal function. These adverse effects are potentially important in clinical situations such as severe abdominal trauma and laparoscopic donor nephrectomy. It was hypothesized that the secondary elevation of ICP leads to release of vasoconstrictors, which may affect renal function by decreasing the renal blood flow (RBF). We investigated the effect of laparoscopy on ICP and renal blood flow in a porcine model. The abdominal pressure of swine (N = 5; 20-25 kg) was gradually increased from baseline to 5, 15, and 25 mm Hg by insufflation of nitrogen into the abdominal cavity. The ICP was measured using a Camino monitor, and RBF was simultaneously measured using a Transonic Doppler probe placed on the renal artery. Results were analyzed using repeated measures ANOVA and the paired t-test. No significant change from baseline was observed in ICP and RBF when the abdominal pressure was 5 mm Hg. However, both ICP and RBF were affected by increasing the abdominal pressure to 15 and 25 mm Hg (P = 0.035 and 0.04 for ICP and P = 0.074 and 0.034 for RBF, respectively). Low-pressure laparoscopy may reduce the adverse effects of pneumoper...Continue Reading

References

Mar 1, 1985·Archives of Internal Medicine·J H SmithT A Raffin
Feb 1, 1983·Annals of Surgery·W O RichardsW Reed
Nov 1, 1982·Annals of Surgery·P K HarmanS P Nolan
Jul 1, 1994·Surgical Endoscopy·Y HashikuraM Makuuchi
Jan 1, 1993·Surgical Endoscopy·S BantingA Cuschieri
Apr 1, 1997·Surgical Endoscopy·R J RosenthalM Grode
Feb 28, 1998·Surgical Endoscopy·J JakimowiczF Smulders
Aug 18, 1999·Surgical Endoscopy·D DavidesM J McMahon
Dec 23, 1999·The Journal of Trauma·J M DotyD A Sica
Jun 17, 2000·Transplantation Proceedings·D RosinA Ayalon
Sep 1, 1947·The Journal of Clinical Investigation·S E Bradley, G P Bradley

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Citations

Apr 2, 2008·Der Urologe. Ausg. A·O GrallaJ Roigas
Dec 16, 2006·World Journal of Urology·O GrallaJ Roigas
Dec 13, 2006·Surgical Endoscopy·Scbastian DemyttenaereGerald M Fried
Apr 23, 2013·Surgical Endoscopy·Chris Westgarth-TaylorJonathan Karpelowsky
Sep 4, 2008·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Julia E Grabowski, Mark A Talamini
Aug 16, 2015·Surgical Endoscopy·Denise M D Özdemir-van BrunschotMichiel C Warlé
Apr 29, 2011·Journal of Intensive Care Medicine·Faisal Al-MufarrejLakhmir S Chawla
Apr 13, 2004·Current Opinion in Critical Care·Manu L N G Malbrain
Jul 22, 2019·Journal of Clinical Monitoring and Computing·Mineto KamataJoseph D Tobias

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