Low prevalence of Chlamydia trachomatis infection in non-urban pregnant women in Vellore, S. India.

PloS One
Navjyot K VidwanValsan Verghese

Abstract

To determine the prevalence and risk factors for Chlamydia trachomatis (CT) infection in pregnant women and the rate of transmission of CT to infants. Pregnant women (≥28 weeks gestation) in Vellore, South India were approached for enrollment from April 2009 to January 2010. After informed consent was obtained, women completed a socio-demographic, prenatal, and sexual history questionnaire. Endocervical samples collected at delivery were examined for CT by a rapid enzyme test and nucleic acid amplification test (NAAT). Neonatal nasopharyngeal and conjunctival swabs were collected for NAAT testing. Overall, 1198 women were enrolled and 799 (67%) endocervical samples were collected at birth. Analyses were completed on 784 participants with available rapid and NAAT results. The mean age of women was 25.8 years (range 18-39 yrs) and 22% (95% CI: 19.7-24.4%) were primigravida. All women enrolled were married; one reported >one sexual partner; and six reported prior STI. We found 71 positive rapid CT tests and 1/784 (0.1%; 95% CI: 0-0.38%) true positive CT infection using NAAT. To our knowledge, this is the largest study on CT prevalence amongst healthy pregnant mothers in southern India, and it documents a very low prevalence with N...Continue Reading

References

May 1, 1989·The Journal of Pediatrics·M R Hammerschlag
Feb 1, 1995·Obstetrics and Gynecology·V SinghD Chattopadhya
Jun 1, 1993·Genitourinary Medicine·R AlexanderP Jasper
Feb 13, 2001·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·V GopalkrishnaB C Das
Apr 5, 2001·Sexually Transmitted Infections·J Mania-PramanikU M Donde
Apr 18, 2001·American Journal of Preventive Medicine·H D Nelson, M Helfand
Feb 5, 2003·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·S RastogiA Mittal
Jun 11, 2003·Archives of Pediatrics & Adolescent Medicine·Marc B RosenmanMartin B Kleiman
Jun 2, 2005·Indian Journal of Medical Microbiology·A G JoyeeM Ganapathy
Jun 20, 2007·Annals of Internal Medicine·UNKNOWN U.S. Preventive Services Task Force
Jul 19, 2008·Fertility and Sterility·Abida MalikSeema Hakim
Oct 28, 2008·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Iyad A El QouqaFadel A Sharif
Oct 31, 2009·Indian Journal of Community Medicine : Official Publication of Indian Association of Preventive & Social Medicine·Savita Sharma, Bp Gupta
Nov 11, 2009·Sexually Transmitted Diseases·Marissa BeckerJames Blanchard
Sep 16, 2011·The Journal of Obstetrics and Gynaecology Research·Aderemi KehindeBabatunde Salako

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Methods Mentioned

BETA
ELISA
PCR
nucleic acid amplification
DNA probe

Software Mentioned

SAS
Statistical Analysis Systems

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