PMID: 9181233Jun 1, 1997Paper

Low-risk differentiated thyroid cancer: the need for selective treatment

Annals of Surgical Oncology
A R ShahaT R Loree

Abstract

The well recognized prognostic factors in differentiated carcinoma of the thyroid are age, grade, extracapsular extension, distant metastasis, and size of the tumor. Based on these prognostic factors, we have divided patients into low-, intermediate-, and high-risk categories. Clearly, there are significant differences in these three groups. This article analyzes in depth our data on low-risk thyroid cancer patients. A retrospective review of 1,038 patients with differentiated carcinoma of the thyroid was undertaken. Various prognostic factors and risk groups were analyzed. Univariate and multivariate analyses were performed, and the survival curves were plotted by the Kaplan-Meier method. The inclusion criteria for the low-risk group were age younger than 45 years, tumors < 4 cm in size, low-grade histology, absence of distant metastasis, and absence of extrathyroidal extension. There were 465 patients in the low-risk group. Four hundred three patients had papillary and 62 patients had follicular thyroid cancer. There were 120 male and 354 female patients. Two hundred seventy-eight patients (60%) presented with clinically apparent lymph node metastasis. With a median follow-up of 20 years, the 10- and 20-year survival in this ...Continue Reading

References

Aug 1, 1979·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·D P ByarM van Glabbeke
Dec 1, 1992·American Journal of Surgery·J P ShahV Vlamis
Dec 1, 1994·Current Problems in Surgery·G H Jossart, O H Clark
Jan 1, 1996·CA: a Cancer Journal for Clinicians·S L ParkerP A Wingo

❮ Previous
Next ❯

Citations

Jul 13, 2016·Journal of Thyroid Research·Amirsina SharifiHossein Mahmoudzade
Jun 1, 2000·Cancer Control : Journal of the Moffitt Cancer Center·A R Shaha
Jun 1, 2000·Cancer Control : Journal of the Moffitt Cancer Center·D S Dean, I D Hay
Jul 13, 2002·Journal of Surgical Oncology·Walter Lawrence, Brian J Kaplan
Jan 27, 2006·Expert Opinion on Biological Therapy·Marius E Kraenzlin, Christian Meier
Nov 30, 2006·Journal of Surgical Oncology·Jack M Monchik, Ronald A DeLellis
Feb 20, 2007·World Journal of Surgery·Ashok R Shaha
Sep 26, 2007·Expert Review of Anticancer Therapy·Adonis T RamirezFausto Chiesa
May 22, 2008·Journal of Surgical Oncology·R Michael TuttleAshok R Shaha
Feb 1, 2013·TheScientificWorldJournal·Raghunandan Venkat, Marlon A Guerrero
Feb 5, 2013·Thyroid : Official Journal of the American Thyroid Association·David F SchneiderRebecca S Sippel
Sep 3, 2013·Indian Journal of Surgical Oncology·Devendra A Chaukar, Abhishek D Vaidya
Jan 28, 2014·Journal of Endocrinological Investigation·D P MomessoM Vaisman
Sep 28, 2018·The British Journal of Radiology·Partha S Choudhury, Manoj Gupta
Feb 24, 2001·American Journal of Medical Quality : the Official Journal of the American College of Medical Quality·S HoelzerJ Dudeck
May 30, 2002·Thyroid : Official Journal of the American Thyroid Association·E Gemsenjäger, Ph U Heitz
Apr 14, 2005·Annals of Surgical Oncology·Philip I HaighLorne E Rotstein
Apr 12, 2007·World Journal of Surgery·Paolo MiccoliFulvio Basolo
Jun 12, 2008·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Jatin P Shah
Apr 10, 2013·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Davor DžepinaHrvoje Čupić
Sep 27, 2013·Endocrine Journal·Makoto KammoriTetsu Yamada
Apr 9, 2015·Thyroid : Official Journal of the American Thyroid Association·James X WuMichael W Yeh
Sep 10, 2014·Annals of the Royal College of Surgeons of England·W L CraigZ H Krukowski
Aug 31, 2017·Thyroid : Official Journal of the American Thyroid Association·Stephen F HallDavid Hurlbut
Jan 1, 2014·Expert Review of Endocrinology & Metabolism·Antonio Sitges-Serra
Oct 9, 1999·The Australian and New Zealand Journal of Surgery·J M ChaplinK Haghighi
Jun 12, 2002·Current Treatment Options in Oncology·J H Yim, G M Doherty
May 28, 2002·Acta Oto-laryngologica·Ashok R ShahaAlessandra Rinaldo
Apr 20, 2004·Nuclear Medicine Communications·Katharine P HoyesErnest Allan
Sep 30, 2009·Thyroid : Official Journal of the American Thyroid Association·Seung-Kuk BaekEun-Jae Chung
Aug 6, 2009·Annals of Surgical Oncology·Stephan A VorburgerChristian A Seiler
Nov 11, 2008·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·R Michael Tuttle
Oct 23, 2014·The Journal of Clinical Endocrinology and Metabolism·Mohamed Abdelgadir AdamJulie A Sosa
Jun 22, 2017·Endocrine Reviews·Megan R HaymartJulia Ann Sosa
Dec 12, 2001·Journal of Evaluation in Clinical Practice·S HoelzerJ Dudeck

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.