PMID: 8948353Oct 1, 1996Paper

Low risk of perioperative infection without prophylactic antibiotics for transperineal prostate brachytherapy

International Journal of Radiation Oncology, Biology, Physics
K E WallnerL Harrison

Abstract

To determine the incidence of postimplant infection in patients who are not given prophylactic antibiotics (ATBs). One hundred thirty-one patients had computerized tomography (CT)-planned transperineal 125I implantation of the prostate from 1988 through 1995. One hundred fourteen of the patients did not receive prophylactic ATBs, 19 of whom required postimplant Foley catheter drainage for 1 day or more for acute urinary retention. The incidence of postimplant febrile episodes within 2 weeks of surgery among the patients who had not received prophylactic ATBs was 2 of 114 (2%). One of the two patients who developed postimplantation febrile episodes was treated successfully with ATBs as an outpatient. The second patient, who had a history of chronic lymphocytic leukemia (CLL) and immune suppression, developed E. coli sepsis and required intravenous antibiotics. Of 17 patients who received prophylactic ATBs, none had a postoperative febrile episode. We continue to refrain from routinely prescribing prophylactic ATBs unless there is some compelling circumstance including rheumatic heart disease, prosthetic devices, immune compromise, or a previous history of prostatitis.

References

Feb 1, 1980·Southern Medical Journal·B I TurnerR K Rhamy
Jul 1, 1994·International Journal of Radiation Oncology, Biology, Physics·K WallnerL Harrison

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Citations

Feb 20, 2004·Urology·S Christopher HoffeltGregory Merrick
Jul 17, 2003·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Amy MuellerSteven Sutlief
Jul 1, 1999·International Journal of Radiation Oncology, Biology, Physics·S NagR Nath
Nov 26, 1999·International Journal of Radiation Oncology, Biology, Physics·S AggarwalW Ellis
Sep 16, 1999·International Journal of Radiation Oncology, Biology, Physics·K WallnerS Sutlief
Feb 4, 2012·Japanese Journal of Radiology·Takeo NomuraHiromitsu Mimata
Feb 19, 2008·The Journal of Urology·J Stuart WolfUNKNOWN Urologic Surgery Antimicrobial Prophylaxis Best Practice Policy Panel
Feb 23, 2021·Brachytherapy·Kevin Martell, Marisa A Kollmeier

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