Low serum high-density lipoprotein cholesterol in childhood is associated with adolescent asthma

Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology
P K YiallourosD K Milton

Abstract

Whilst emerging evidence from animal and cell experiments has shown high-density lipoprotein cholesterol to have anti-inflammatory effects consistent with a protective role in asthma, human studies investigating the relationship of high-density lipoprotein cholesterol with asthma have produced conflicting results. To examine the association between serum lipids among Cypriot children aged 11-12 years and prevalence of asthma at age 15-17 years. In 3982 children, we assessed serum lipids, body mass index and maximal oxygen consumption at baseline (2001-2003) and explored associations with respiratory health at follow-up (2007) using multiple logistic regression models. Lower levels of high-density lipoprotein cholesterol at age 11-12 years were found in subjects who reported ever asthma (58.2 vs. 60.0 mg/dL, P = 0.005) and active asthma (57.5 vs. 59.9 mg/dL, P = 0.010) in adolescence, in comparison with their respective reference groups. Total cholesterol, low-density lipoprotein and triglycerides had no association with any of the asthma outcomes. In contrast, with estimated odds ratios of 1.89 (95% CI 1.19-3.00) and 1.89 (95% CI 1.02-3.53), ever asthma and active asthma respectively appeared particularly pronounced among those...Continue Reading

References

May 1, 1989·The American Journal of Clinical Nutrition·G Georgiades, V Klissouras
Jan 1, 1988·Journal of Sports Sciences·L A LégerJ Lambert
May 1, 1993·Proceedings of the National Academy of Sciences of the United States of America·T A Voyno-YasenetskayaR L Hamilton
Jan 1, 1996·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·P L EnrightE C Lasser
Oct 9, 1999·Free Radical Biology & Medicine·I KolleckB Rüstow
May 17, 2000·Current Opinion in Pulmonary Medicine·C J Clark, L M Cochrane
Apr 30, 2002·American Journal of Epidemiology·Dominic J CirilloPatricia A Cassano
Jun 6, 2002·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·D JarvisUNKNOWN European Community Respiratory Health Survey
Oct 11, 2002·Free Radical Biology & Medicine·Karen Y StokesD Neil Granger
Apr 25, 2003·The Journal of Pediatrics·Rae-Ellen W KaveyUNKNOWN American Heart Association
Oct 2, 2003·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·T SchäferJ Ring
Dec 4, 2004·The Journal of Allergy and Clinical Immunology·Tricia M McKeeverPatricia A Cassano
Jun 7, 2006·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Baha Al-ShawwaMutasim Abu-Hasan
Sep 1, 2007·Medicine and Science in Sports and Exercise·Joey C EisenmannJames Dollman
Sep 1, 2007·International Journal of Pediatric Obesity : IJPO : an Official Journal of the International Association for the Study of Obesity·Joey C EisenmannSteven N Blair
Sep 20, 2007·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·B N LaerumC Svanes
Dec 1, 2007·Allergologia et immunopathologia·F ErelM Karaayvaz
Mar 25, 2008·The American Journal of Cardiology·Michael MillerErnst J Schaefer
May 9, 2008·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·L Garcia-MarcosA Garcia-Merino
Jul 4, 2008·Pediatrics·Stephen R DanielsUNKNOWN Committee on Nutrition
Jul 12, 2008·Arteriosclerosis, Thrombosis, and Vascular Biology·Andrew J MurphyJaye Chin-Dusting
Sep 30, 2008·American Journal of Physiology. Lung Cellular and Molecular Physiology·Christopher J DelvecchioJohn P Capone
Oct 24, 2008·Arteriosclerosis, Thrombosis, and Vascular Biology·Kerry-Anne Rye, Philip J Barter
Jan 13, 2009·The Journal of Allergy and Clinical Immunology·Fengxiu OuyangXiaobin Wang
Jan 27, 2009·American Journal of Physiology. Lung Cellular and Molecular Physiology·Hiroshi OteraYoshihiro Nishimura
Feb 10, 2009·Current Medicinal Chemistry·A J MurphyK J Woollard
Feb 17, 2009·International Archives of Allergy and Immunology·Gabriele NagelWolfgang Koenig
Aug 20, 2009·Public Health Nutrition·Leda Chatzi, Manolis Kogevinas
Oct 6, 2009·The Journal of Allergy and Clinical Immunology·Michael B FesslerDarryl C Zeldin
Aug 20, 2010·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·C S MurrayA Custovic
Dec 1, 2010·The Journal of Immunology : Official Journal of the American Association of Immunologists·Xianglan YaoStewart J Levine
Dec 16, 2010·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·C M Salome, G B Marks

❮ Previous
Next ❯

Citations

Mar 26, 2013·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Jayanthi VijayakumarAhmed Tawakol
Oct 1, 2013·Respiratory Medicine·Nicola ScichiloneVincenzo Bellia
Feb 24, 2012·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·M B Fessler
Aug 22, 2012·The Clinical Respiratory Journal·Finn RasmussenMads Nybo
Feb 19, 2015·American Journal of Respiratory and Critical Care Medicine·Amisha V BarochiaStewart J Levine
Dec 10, 2013·International Journal of Cardiology·Daniel P Potaczek
Nov 27, 2015·Translational Research : the Journal of Laboratory and Clinical Medicine·Cong-Lin LiuGuo-Ping Shi
Apr 27, 2016·Allergologia et immunopathologia·L-J FangK-S Wan
Sep 14, 2016·Immunity, Inflammation and Disease·Muriel SmetJohan Grooten
Sep 26, 2017·Current Medical Research and Opinion·Xinming SuJian Kang
Mar 20, 2015·World Journal of Clinical Cases·Laura Serafino-AgrusaNicola Scichilone
Aug 9, 2019·Lipids in Health and Disease·Tianrong ZhangLin Ye
Nov 25, 2020·Arteriosclerosis, Thrombosis, and Vascular Biology·Christian M MadsenBørge G Nordestgaard
Jul 11, 2021·Cell Biochemistry and Biophysics·Patrick J OliverNarasimham L Parinandi

❮ Previous
Next ❯

Related Concepts

Related Feeds

Asthma

This feed focuses in Asthma in which your airways narrow and swell. This can make breathing difficult and trigger coughing, wheezing and shortness of breath.

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.

ApoE, Lipids & Cholesterol

Serum cholesterol, triglycerides, apolipoprotein B (APOB)-containing lipoproteins (very low-density lipoprotein (VLDL), immediate-density lipoprotein (IDL), and low-density lipoprotein (LDL), lipoprotein A (LPA)) and the total cholesterol/high-density lipoprotein (HDL) cholesterol ratio are all connected in diseases. Here is the latest research.

Related Papers

The Journal of Allergy and Clinical Immunology
Michael B FesslerD C Zeldin
Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology
T SchäferJohannes Ring
Pulmonary Pharmacology & Therapeutics
Kymberly M Gowdy, Michael B Fessler
© 2022 Meta ULC. All rights reserved