PMID: 6401508Jan 8, 1983Paper

Low serum testosterone concentrations in patients with carcinoma of the pancreas

British Medical Journal
B A GreenwayR Williams

Abstract

The detection of high activities of two sex-steroid biosynthetic enzymes-aromatase and 5-alpha-reductase-in pancreatic carcinoma tissue suggested the possibility that these enzymes may influence the circulating concentrations of sex-steroid hormones. Mean serum testosterone concentrations in 22 men and women with exocrine carcinoma of the pancreas were significantly lower than those in 20 healthy controls and 27 patients with other known malignancies, who were of similar age and sex composition. Low serum testosterone concentrations may be due to uptake by and metabolism within the tumour; alternatively, patients with low androgen concentrations may be at greater risk of developing pancreatic carcinoma.

References

Oct 1, 1979·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·D Y WangJ L Hayward
Jan 1, 1976·Journal of Surgical Oncology·P H SugarbakerN Zamcheck
Mar 1, 1972·Clinica Chimica Acta; International Journal of Clinical Chemistry·M L DufauD Ryan
Dec 1, 1974·British Journal of Cancer·P C EnglandR A Sellwood
Apr 1, 1972·Journal of Steroid Biochemistry·W P CollinsI F Sommerville
Apr 1, 1972·The Journal of Clinical Endocrinology and Metabolism·A VermeulenL Verdonck
Mar 1, 1972·Acta Endocrinologica·Y Emment, W P Collins
Sep 19, 1981·British Medical Journal·B GreenwayR Williams
Oct 1, 1982·The British Journal of Surgery·B GreenwayR Williams
Aug 1, 1981·European Journal of Cancer & Clinical Oncology·W R MillerA P Forrest

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Citations

Jan 1, 1996·Journal of Cancer Research and Clinical Oncology·M MagnantiV Santiemma
Sep 1, 2005·Investigational New Drugs·Sanjay Singh NegiAdarsh Chaudhary
Oct 1, 1996·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·G Mendoza-HernándezJ L Rendón
Dec 1, 1990·Baillière's Clinical Gastroenterology·J M Rhodes, C K Ching
Dec 1, 1990·Baillière's Clinical Gastroenterology·A Andrén-Sandberg, P L Bäckman
Jan 20, 1999·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·P StoneJ Hardy
Jan 1, 1984·Proceedings of the National Academy of Sciences of the United States of America·T W Redding, A V Schally
Dec 3, 1988·BMJ : British Medical Journal·Z TulassayT Fehér
Jul 1, 1991·Gut·G J PostonP J Guillou
Jun 10, 2004·Reviews on Environmental Health·Chikako KiyoharaJulian M Hopkin
Sep 1, 1996·The Journal of Dermatology·T EbataM Niimura
Aug 1, 1993·Respiratory Medicine·D P TaggartK G Davidson
May 16, 1996·International Journal of Cancer. Journal International Du Cancer·B T JiJ F Fraumeni
Jun 1, 1987·The British Journal of Surgery·B A Greenway
Jul 1, 1984·British Journal of Haematology·W O SchreuderA Jacobs
Mar 1, 1986·Scandinavian Journal of Gastroenterology·A Andrén-Sandberg
Apr 15, 1988·Biochemical and Biophysical Research Communications·G Mendoza-HernándezJ C Díaz-Zagoya
Apr 1, 1992·International Journal of Pancreatology : Official Journal of the International Association of Pancreatology·M MeijersR A Woutersen
Aug 1, 1990·International Journal of Pancreatology : Official Journal of the International Association of Pancreatology·A Andrén-Sandberg, J Johansson
May 1, 1989·International Journal of Pancreatology : Official Journal of the International Association of Pancreatology·A Andrén-Sandberg

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