PMID: 42654Dec 1, 1979

Low strength anthralin in psoriasis

Journal of Cutaneous Pathology
L F MontesI Brody

Abstract

Anthralin in low concentrations (0.01%--0.03%) was applied in an ointment form once per day in the hospital to 130 psoriasis patients. The treatment program included also the use of UVB light, emollients and bath oil and an antihistamine. Clearing of psoriasis was achieved in all patients in an average time of 4 weeks. The involution of the lesions was carefully studied by correlated clinical observations, light microscopy, transmission electron microscopy (TEM) and scanning electron microscopy (SEM). Striking healing of the holes in the stratum corneum and of the gaps in the basement membrane occurred. Low strength anthralin, in addition to its effectiveness, did not produce irritation, staining or side-effects.

References

Oct 6, 1997·Clinics in Dermatology·G Mahrle
Feb 1, 1981·Journal of the American Academy of Dermatology·B Thiers
Jul 1, 1981·Journal of the American Academy of Dermatology·R J Coskey
Mar 1, 1983·Journal of the American Academy of Dermatology·E M FarberA Charuworn
Aug 1, 1983·Journal of the American Academy of Dermatology·R E AshtonM Whitefield
Oct 13, 2006·Skin Pharmacology and Physiology·A WozniackaA Sysa-Jedrzejowska

Citations

Oct 1, 1977·Journal of Cutaneous Pathology·I Brody, A Johansson
Apr 12, 1979·The New England Journal of Medicine·R S SternT B Fitzpatrick
Jan 1, 1975·Journal of Cutaneous Pathology·I Brody
Apr 1, 1970·Archives of Dermatology·E M Farber, D R Harris
Jan 1, 1974·Journal of Cutaneous Pathology·W H Wilborn, L F Montes
Jan 1, 1974·Journal of Cutaneous Pathology·I BrodyM Matsunaka
May 1, 1970·The Journal of Investigative Dermatology·D L Baxter, R B Stoughton
Oct 1, 1945·Archives of Dermatology and Syphilology·A C CURTIS, B B OWENS

Related Concepts

Psoriasis
Polychemotherapy
Anthrones
Antihistamines, Classical
Electron Microscopy
Oils
Skin
Clinical Trials
Paste Substance
Photochemotherapy

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