Low Systolic Blood Pressure From Treatment and Association With Serious Falls/Syncope

American Journal of Preventive Medicine
John J SimKristi Reynolds

Abstract

With the growing emphasis on intensive blood pressure control, the potential for overtreatment and treatment-related adverse outcomes has become an area of interest. A large representative population within a real-world clinical environment with successful hypertension control rates was used to evaluate serious falls and syncope in people with low-treated systolic blood pressure (SBP). A cross-sectional study among medically treated hypertensive individuals within the Kaiser Permanente Southern California health system (2014-2015) was performed. Serious fall injuries and syncope were identified using ICD codes based on emergency department and hospitalization diagnoses. SBPs in a 1-year window were used to compare serious falls and syncope among individuals with SBP <110 mmHg vs ≥110 mmHg. Logistic regression was used to evaluate the association between low minimum and mean SBP and serious falls/syncope after adjustment for demographics, comorbidities, and medications. In 477,516 treated hypertensive individuals, the mean age was 65 (SD=13) years and the mean SBP was 129 (SD=10) mmHg, with 27% having a minimum SBP <110 mmHg and 3% having mean SBP <110 mmHg. A total of 15,419 (3.2%) individuals experienced a serious fall or sync...Continue Reading

Citations

Apr 14, 2020·International Journal of Geriatric Psychiatry·Anthony YeungDamien Gallagher
Feb 11, 2021·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Giulia RivasiArtur Fedorowski
Oct 4, 2020·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Hui ZhouSteven J Jacobsen
Jun 18, 2021·BMC Geriatrics·Stijn CrutzenKatja Taxis

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