Low total and nonheme iron intakes are associated with a greater risk of hypertension

The Journal of Nutrition
P GalanS Hercberg

Abstract

The relationship between iron intake and blood pressure (BP) status has not been well established. Only 1 cross-sectional study has suggested an inverse association of dietary total iron intake and nonheme iron intake with BP. We investigated the relationship between total, heme, and nonheme iron intakes, markers of iron status, 5.4-y changes in BP, and the incidence of hypertension. A total of 2895 participants included in the Supplémentation en Vitamines et Minéraux Antioxydants cohort were followed up for 5.4 y. At least 3 repeated 24-h dietary records were performed at baseline and 5.4 y later. Hemoglobin and serum ferritin concentrations were assessed at baseline. Low nonheme iron intake at baseline was associated with a greater increase in systolic BP (SBP) and pulse pressure over time after adjustment for multiple possible confounding factors (P-trend = 0.002 and 0.0005, respectively). Conversely, participants in the 3rd tertile of nonheme iron intake at baseline had a 37% lower risk of hypertension after 5.4 y of follow-up compared with those in the first tertile (P-trend = 0.04). Heme iron intake was not associated with BP changes or risk of hypertension. Meat intake was positively associated with an increase in SBP (P...Continue Reading

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Citations

Nov 29, 2013·BMC Complementary and Alternative Medicine·Catherine A McCartyRichard A Dart
Aug 16, 2011·Journal of Women's Health·Edoardo CasigliaPaolo Palatini
Dec 22, 2015·Journal of Atherosclerosis and Thrombosis·Queenie ChanPaul Elliott
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Mar 6, 2018·Nutrition Reviews·Malgorzata A DesmondJonathan C K Wells
Dec 14, 2017·Critical Reviews in Food Science and Nutrition·Noushin MohammadifardNizal Sarrafzadegan

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