Low-volume resistance exercise attenuates the decline in strength and muscle mass associated with immobilization

Muscle & Nerve
Bryan R OatesStuart M Phillips

Abstract

We determined the effectiveness of low-volume resistance exercise (EX) for the attenuation of loss of muscle mass and strength during leg immobilization. Men (N = 5) and women (N = 12, age 24 ± 5 years, body mass index 25.4 ± 3.6 kg/m(2)) were divided into two groups: exercise (EX; n = 12) and control (CON; n = 5). Subjects wore a knee brace on one leg that prevented weight bearing for 14 days. Resistance exercise (EX; 80% of maximal) was performed by the immobilized limb every other day. Immobilization induced a significant reduction (P < 0.05) in muscle fiber and thigh cross-sectional area (CSA), isometric knee extensor, and plantarflexor strength in the CON (P < 0.01) but not in the EX group. There were significant losses in triceps surae CSA in the CON and EX groups (P < 0.05), but the losses were greater in CON subjects (P < 0.01). A minimal volume (140 contractions in 14 days) of resistive exercise is an effective countermeasure against immobilization-induced atrophy of the quadriceps femoris but is only partially effective for the triceps surae.

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Citations

Nov 23, 2011·European Journal of Applied Physiology·Daniel W D West, Stuart M Phillips
Apr 21, 2012·Journal of Applied Physiology·Cameron J MitchellStuart M Phillips
Aug 5, 2011·Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine·Renu B Pattanshetty, Gajanan S Gaude
Dec 17, 2014·The Journal of Physiology·Stuart M Phillips, Chris McGlory
Jul 1, 2014·Scandinavian Journal of Medicine & Science in Sports·F MersmannA Arampatzis
Jul 17, 2014·European Journal of Sport Science·Benjamin T WallLuc J C van Loon
Jan 16, 2019·American Journal of Physiology. Endocrinology and Metabolism·Marlou L DirksLuc J C van Loon
Apr 5, 2018·Frontiers in Physiology·Yunfang GaoNandu Goswami
Jun 11, 2019·Frontiers in Nutrition·Sara Y OikawaStuart M Phillips
Jun 13, 2014·The Journal of Nutrition·Marlou L DirksLuc J C van Loon
Jun 29, 2012·American Journal of Physiology. Endocrinology and Metabolism·Benjamin T WallLuc J C van Loon
Mar 24, 2017·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·Carlos K KatashimaGustavo D Pimentel
Mar 23, 2019·Sports Medicine·Matthew CampbellJoanna L Bowtell
Jul 30, 2019·Frontiers in Nutrition·Tanya M HollowayStuart M Phillips
Oct 8, 2020·The Proceedings of the Nutrition Society·Colleen S DeanePhilip J Atherton
Jan 12, 2021·Physiological Reports·Rob J MacLennanMatt S Stock
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Oct 27, 2020·Medicine and Science in Sports and Exercise·Joshua T SlyszJamie F Burr
Apr 1, 2021·Medicine and Science in Sports and Exercise·Lasse GliemannYlva Hellsten

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