Lower esophageal sphincter pressure in Chagas' disease

Digestive Diseases and Sciences
R O DantasL E Troncon

Abstract

It is known that lower esophageal sphincter (LES) pressure in patients with idiopathic achalasia is higher than in normal subjects, but in patients with Chagas' disease, who have esophageal disease with similar clinical, manometric, and radiologic results, studies of LES pressure show contradictory findings. We measured the LES pressure in 118 patients with chronic Chagas' disease, 14 patients with idiopathic achalasia, and 50 control subjects using a perfused catheter and the stationary pull-through (SPT) technique. The patients with Chagas' disease had normal esophageal radiologic examination (group A, N = 50), delay in esophageal clearance without dilatation (group B, N = 41), or delay in esophageal clearance with dilatation (group C, N = 27). The LES pressure of Chagas' disease patients of group A (18.6 +/- 9.1 mm Hg, mean +/- SD), group B (17.8 +/- 9.7 mm Hg), and group C (21.6 +/- 10.1 mm Hg) was lower (P less than 0.001) than the LES pressure of the controls (24.9 +/- 10.2 mm Hg). In patients with idiopathic achalasia, the LES pressure (40.7 +/- 17.8 mm Hg) was higher than in control subjects (P less than 0.01) and Chagas' disease patients (P less than 0.001). We conclude that the LES pressure of patients with Chagas' di...Continue Reading

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Citations

May 1, 1993·Digestive Diseases and Sciences·R O Dantas, M G Villanova
Jul 1, 1993·Digestive Diseases and Sciences·S StupnikA García
Dec 11, 2002·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·R O Dantas
May 26, 1998·Journal of Clinical Gastroenterology·M A Nobre e Souza, R O Dantas
Jan 20, 2009·Current Problems in Surgery·Thomas J WatsonVirginia R Litle
Sep 21, 2006·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·R I RamosR O Dantas
Dec 21, 2010·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·L J Abrahão, E M de Oliveira Lemme
Oct 24, 2012·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·J M Remes-TrocheE De-La-Cruz-Patiño
Jul 1, 1997·Revista Do Instituto De Medicina Tropical De São Paulo·L C de OliveiraE C Salomão
Apr 25, 2000·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·R O Dantas
Jun 5, 2002·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·R O DantasA L M Miranda
Mar 1, 2002·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·E M LemmeJ Pantoja
Jul 1, 1998·The American Journal of Gastroenterology·R B de OliveiraU G Menghelli
Mar 31, 2004·Revista Da Sociedade Brasileira De Medicina Tropical·Eduardo CremaAlex Augusto Silva
Apr 16, 2021·Dysphagia·Roberto Oliveira Dantas

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