Lower gastrointestinal symptoms are prevalent among individuals colonoscoped within the Bowel Cancer Screening Programme

Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland
P T RajasekharC J Rees

Abstract

The National Health Service Bowel Cancer Screening Programme (BCSP) aims to detect earlier stage cancer in asymptomatic individuals. Early experience suggested that many participants had lower gastrointestinal symptoms before screening. The study evaluated the prevalence of lower gastrointestinal symptoms and consultation behaviour among individuals undergoing colonoscopy at the South of Tyne BCSP Centre. Data were collected on all undergoing clinic assessment and colonoscopy. Symptoms were categorized as altered bowel habit (ABH), rectal bleeding (RB), abdominal pain (AP) and unexplained weight loss (UWL). Symptoms were present in 65.1% (492/756) of subjects, 64.4% (431/669) of those with a non-cancer diagnosis and 70.1% (61/87) of those with cancer. Among those with a non-cancer diagnosis, symptoms were ABH in 52% (224/431), RB in 81.4% (351/431), AP in 15.3% (66/431) and UWL in 3.0% (13/431). In those with cancer symptoms they were ABH in 33.3% (29/87), RB in 55.2% (48/87) and AP in 11.5% (10/87). There was no significant difference in the prevalence of symptoms in those with a cancer or non-cancer diagnosis. A total of 34.2% (157/459) of individuals with symptoms had consulted their general practitioner, 28.1% (16/57) of th...Continue Reading

References

Aug 19, 1995·BMJ : British Medical Journal·A Crosland, R Jones
Sep 11, 2002·Gut·W S AtkinUNKNOWN Association of Coloproctology for Great Britain and Ireland
Apr 8, 2004·Journal of the National Cancer Institute·Mary B BartonSuzanne W Fletcher
Jul 9, 2004·BMJ : British Medical Journal·UNKNOWN UK Colorectal Cancer Screening Pilot Group
Aug 5, 2004·Journal of the National Cancer Institute·Daniel B Kopans
Aug 9, 2008·Social Science & Medicine·Sheina OrbellDavid Weller
Feb 18, 2009·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·C HarmstonL Wong
Sep 25, 2009·Health Statistics Quarterly·Christopher Hill
Oct 22, 2009·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·P EllulA M Veitch
Feb 27, 2010·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·Alex Almoudaris, Omar Faiz

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Citations

Apr 10, 2014·Clinical Medicine : Journal of the Royal College of Physicians of London·Praveen RajasekharPali Hungin
Oct 10, 2013·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·P G Vaughan-ShawJ M D Wheeler
Feb 27, 2014·Asian Pacific Journal of Cancer Prevention : APJCP·Gui-Xian TongDe-Bin Wang
Jun 1, 2019·World Journal of Gastroenterology : WJG·Noel Pin VieitoJoaquín Cubiella

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