Abstract
To study prevalence of lower genital tract infections (LGTI) (bacterial vaginosis, trichomoniasis, and candidiasis) in HIV-seropositive women and correlation with CD4 counts and antiretroviral therapy (ART). Cross-sectional study conducted in 200 HIV-1-seropositive women (18 to 45 years) attending ART clinic of PGIMS, Rohtak. Vaginal samples sent for laboratory diagnosis of bacterial vaginosis, trichomoniasis, and candidiasis, CD4 count determined and data analyzed using Chi-square method. Prevalence of bacterial vaginosis, candidiasis, and trichomoniasis was 47.7, 43.2, and 8.8 % respectively, 30 % women with CD4 counts <200 cells/μl had LGTI, and 17.4 % women with CD4 >200 Cell/μl had LGTI. Of 70 women not on ART, 18.6 % had LGTI and 30 of 130 on ART had LGTI. HIV-seropositive women had higher prevalence of LGTI especially at lower CD4 counts and women on ART did not have a lower prevalence of LGTI and should be screened for LGTI to decrease HIV transmission.
References
Mar 10, 2001·The Journal of Infectious Diseases·C C WangJ K Kreiss
Aug 21, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·S Cu-UvinUNKNOWN HIV Epidemiology Research Study
Aug 23, 2001·Infectious Diseases in Obstetrics and Gynecology·D WarrenUNKNOWN HIV Epidemiology Research Study Group
Dec 14, 2004·The Journal of Infectious Diseases·Beverly E ShaGregory T Spear
Jan 6, 2005·The Journal of Infectious Diseases·R Scott McClellandJared M Baeten
Mar 5, 2005·American Journal of Obstetrics and Gynecology·Arsenio SpinilloRenato Maserati
Feb 16, 2008·The Journal of Infectious Diseases·Barbara Van Der PolCharles S Morrison
Jul 11, 2008·AIDS·Julius AtashiliJennifer S Smith
Nov 15, 2008·Sexually Transmitted Diseases·Patricia KissingerDavid H Martin
Jan 16, 2009·Revista brasileira de ginecologia e obstetrícia : revista da Federação Brasileira das Sociedades de Ginecologia e Obstetrícia·Paula Matos OliveiraMaria Fernanda Rios Grassi
Jun 30, 2009·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·C TibaldiC Benedetto
Sep 8, 2009·Sexually Transmitted Diseases·Jenifer E AllsworthJeffrey F Peipert
Apr 29, 2011·Anaerobe·Jeanne M Marrazzo
Oct 25, 2011·Indian Journal of Sexually Transmitted Diseases and AIDS·Vandana GoelY M Mala
Mar 6, 2012·Current HIV Research·Paria MirmonsefGregory T Spear