Lower genital tract swabs in the prediction of intrauterine infection in preterm prelabour rupture of the membranes

British Journal of Obstetrics and Gynaecology
S G CarrollK H Nicolaides

Abstract

To examine the genital tract flora in women with preterm prelabour rupture of the membranes and to determine the relationship of these microorganisms to those found in fetal blood and amniotic fluid. Prospective study of 97 patients with preterm prelabour rupture of the membranes. Maternal-fetal medicine centre. High vaginal and endocervical swabs were taken for routine culture of aerobic and anaerobic bacteria and Ureaplasma urealyticum and Mycoplasma hominis. Cordocentesis and amniocentesis were performed and fetal blood and amniotic fluid were cultured for aerobic and anaerobic bacteria. Amniotic fluid was also cultured for Mycoplasma spp. The sensitivities and specificities of genital tract colonisation in the prediction of fetal blood and amniotic fluid infection were calculated. Positive genital tract cultures for aerobic and anaerobic organisms predicted 40% of positive fetal blood and 53% of positive amniotic fluid cultures with false positive rates of 24% and 25%, respectively. The sensitivity and false positive rates for genital tract colonisation with Mycoplasma spp in the prediction of amniotic fluid infection with these organisms were 85% and 35%, respectively. In preterm prelabour rupture of the membranes lower ge...Continue Reading

References

Jan 15, 1979·American Journal of Obstetrics and Gynecology·R F HarrisonJ deLouvois
Oct 23, 1976·British Medical Journal·R W RushA C Turnbull
Nov 1, 1992·American Journal of Obstetrics and Gynecology·L L Coultrip, J H Grossman
Mar 1, 1992·British Journal of Obstetrics and Gynaecology·H M McDonaldP J McDonald
Nov 1, 1991·The Australian & New Zealand Journal of Obstetrics & Gynaecology·J DudleyD Ellwood
Jul 1, 1991·Archives of Disease in Childhood·D James
Apr 1, 1990·The Pediatric Infectious Disease Journal·R L Wientzen
Nov 1, 1990·American Journal of Obstetrics and Gynecology·J A McGregorJ Schoonmaker
Aug 1, 1989·European Journal of Obstetrics, Gynecology, and Reproductive Biology·H J VonséeC P van Boven
Aug 1, 1989·The Australian & New Zealand Journal of Obstetrics & Gynaecology·H McDonaldJ A O'Loughlin
Jun 1, 1986·British Journal of Obstetrics and Gynaecology·T M Scane, D F Hawkins
Apr 1, 1987·American Journal of Obstetrics and Gynecology·R L SweetJ Schachter
Sep 1, 1988·American Journal of Obstetrics and Gynecology·R RomeroJ C Hobbins
Jan 1, 1987·American Journal of Obstetrics and Gynecology·I A AbbasiT R Johnson
Mar 15, 1985·American Journal of Obstetrics and Gynecology·J R BobittJ Sakakini
Nov 1, 1970·Journal of Medical Microbiology·A H DaddA C Jones
Dec 15, 1984·American Journal of Obstetrics and Gynecology·H MinkoffW M McCormack
Oct 7, 1983·JAMA : the Journal of the American Medical Association·H R HarrisonD A Sim
Jan 1, 1982·The Journal of Infectious Diseases·R S GibbsY S Castaneda
Aug 1, 1982·American Journal of Obstetrics and Gynecology·J D BlancoY S Castaneda
Jan 1, 1995·Archives of Disease in Childhood. Fetal and Neonatal Edition·S G CarrollK H Nicolaides
Feb 1, 1994·American Journal of Obstetrics and Gynecology·V L KatzS D Wells
Aug 1, 1993·American Journal of Obstetrics and Gynecology·J A McGregorK Seo
Jan 1, 1993·Clinical Microbiology Reviews·G H CassellR Harasawa

❮ Previous
Next ❯

Citations

Dec 7, 2002·Obstetrics and Gynecology·Sarah E FergusonMark C Walker
Oct 19, 2006·Mediators of Inflammation·Ariadne Malamitsi-PuchnerDemetrios Hassiakos
Dec 3, 2009·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Francesca GotschLami Yeo
Oct 18, 2011·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Sun Min KimBo Hyun Yoon
Jul 10, 2014·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Gali ParienteReli Hershkovitz
Mar 16, 2013·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Tamara StampalijaTinnakorn Chaiworapongsa
Sep 4, 2014·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Sun Min KimBo Hyun Yoon
Sep 23, 2014·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·P AroraV Gautam
Dec 4, 2015·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Sun Min KimBo Hyun Yoon
Mar 29, 2002·Mental Retardation and Developmental Disabilities Research Reviews·Luís F GonçalvesRoberto Romero
Jan 8, 2008·Lancet·Robert L GoldenbergRoberto Romero
Oct 3, 2015·American Journal of Obstetrics and Gynecology·Chong Jai KimYeon Mee Kim
Jan 9, 2007·BJOG : an International Journal of Obstetrics and Gynaecology·R RomeroM Mazor
Apr 24, 2007·Best Practice & Research. Clinical Obstetrics & Gynaecology·M Al-Adnani, N J Sebire
Oct 20, 2004·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·A M BaharM A Eskander
Aug 30, 2011·Journal of Medical Microbiology·Cecilia Gonzales-MarinRobert P Allaker
Feb 1, 2015·American Journal of Obstetrics and Gynecology·Matthew Josiah Allen-DanielsKimberly K Jefferson
Aug 15, 1998·American Journal of Obstetrics and Gynecology·R RomeroS M Berry
Oct 31, 2003·American Journal of Obstetrics and Gynecology·Gregor Reid, Alan Bocking
Aug 25, 2001·Paediatric and Perinatal Epidemiology·R RomeroY M Kim
Jan 19, 2017·Journal of Perinatal Medicine·Gilbert G G DondersLjubomir Petricevic
Dec 28, 2005·Journal of the Society for Gynecologic Investigation·Ariadne Malamitsi-PuchnerGeorge Creatsas
Aug 31, 2013·Journal of Perinatology : Official Journal of the California Perinatal Association·G J ChanS K Saha
Oct 12, 2000·BJOG : an International Journal of Obstetrics and Gynaecology·V C HeathK H Nicolaides
Feb 20, 2007·Annals of the New York Academy of Sciences·Ariadne Malamitsi-PuchnerDimitrios Hassiakos
Apr 17, 2013·Current Opinion in Infectious Diseases·Romina CapocciaDavid Baud
Apr 27, 2021·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Imane Ben M'BarekLaurent Mandelbrot

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.