Lower risk of primary Sjogren's syndrome in patients with dengue virus infection: a nationwide cohort study in Taiwan.

Clinical Rheumatology
Chi-Ching ChangChyi-Huey Bai

Abstract

The data concerning the association between dengue viruses (DV) infection and autoimmune diseases (ADs) remain unclear and are scarce. This nationwide population-based cohort study assessed the risk of ADs among patients with DV infection. We analyzed Taiwanese medical data from the Registry of the National Notifiable Disease Reporting System of Taiwan's Centers for Disease Control between 1998 and 2015 and identified patients with DV infection. From the entire general population data in the National Health Insurance Research Database, we randomly selected a comparison cohort that was individual matching by age, sex, residence, and index date. We analyzed the risk of ADs using a Cox proportional hazards regression model stratified by sex, age, and residence. We enrolled 29,365 patients with DV infection (50.68% men; mean age, 44.13 years) and 117,460 age-, sex-, and residence-matched controls in the present study. The incidence rates of organ-specific ADs were nonsignificantly higher in the DV cohort than in the non-DV control cohort. An approximately 70% lower risk of primary Sjogren syndrome (pSS) was evident in the DV cohort than in the non-DV control cohort with an adjusted hazard ratio of 0.30 (95% confidence interval 0.13...Continue Reading

References

Feb 20, 1975·The New England Journal of Medicine·A Bohan, J B Peter
Feb 13, 1975·The New England Journal of Medicine·A Bohan, J B Peter
Feb 1, 1990·Proceedings of the National Academy of Sciences of the United States of America·C O JacobH Acha-Orbea
Jun 8, 2001·The Journal of Immunology : Official Journal of the American Association of Immunologists·U ChristenM G von Herrath
May 15, 2002·Annals of the Rheumatic Diseases·C VitaliUNKNOWN European Study Group on Classification Criteria for Sjögren's Syndrome
May 22, 2002·Annals of the New York Academy of Sciences·Rolf M Zinkernagel
Jan 1, 2004·The Journal of Clinical Investigation·Urs ChristenMatthias G von Herrath
Oct 1, 2004·Arthritis and Rheumatism·Antigoni TriantafyllopoulouHaralampos M Moutsopoulos
Jun 10, 2005·The Journal of Immunology : Official Journal of the American Association of Immunologists·Urs Christen, Matthias G von Herrath
Jul 5, 2006·Viral Immunology·Chiou-Feng LinYee-Shin Lin
Feb 16, 2008·Journal of Autoimmune Diseases·Masha Fridkis-Hareli
Oct 14, 2009·Clinical Microbiology Reviews·Byron E E MartinaAlbert D M E Osterhaus
Apr 27, 2010·Clinical and Experimental Immunology·H OkadaJ-F Bach
Jul 20, 2010·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Suchitra Ranjit, Niranjan Kissoon
Nov 30, 2010·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Gissel GarcíaMaria G Guzmán
Apr 15, 2011·Arthritis Research & Therapy·Nikolaos V SipsasHaralampos M Moutsopoulos
Apr 13, 2012·The New England Journal of Medicine·Cameron P SimmonsBridget Wills
Jan 22, 2013·Journal of the Formosan Medical Association = Taiwan Yi Zhi·Shu-Wen WanYee-Shin Lin
Mar 19, 2014·Journal of Autoimmunity·Shaye KivityNancy Agmon-Levin

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