PMID: 8938612Oct 1, 1996Paper

Lumbar disc degeneration and sagittal flexibility

Journal of Spinal Disorders
A K BurtonK M Tillotson

Abstract

It is uncertain whether intervertebral disc degeneration is associated with reduced or increased flexibility, although lumbar flexibility is known to reduce with advancing age. This cross-sectional study of 214 middle-aged men attempted to determine the influence on lumbar sagittal flexibility from intervertebral disc degeneration parameters measured from magnetic resonance images (disc height, signal intensity, bulging, osteophytes). Multivariate analyses showed that a reduced extent of lumbar flexibility could be accounted for by the combined effect of decreasing disc height together with increasing age, weight, and back pain frequency. Although it remains possible that single degenerate discs will display increased mobility, the presence of discs at various stages of degeneration results in a net reduction of flexibility. The factors studied here explained only 31% of the variance in flexibility; the major determinants remain to be identified and quantified.

Citations

Jan 18, 2006·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Robert C Mulholland
Dec 5, 2006·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Christoph QuackAndreas Klipstein
Dec 22, 2009·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Robert C Mulholland
Mar 14, 2012·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Donal McNallyScott Johnson
Dec 16, 2003·Journal of Manipulative and Physiological Therapeutics·Tony S KellerRobert Gunzburg
Jan 24, 2004·Journal of Manipulative and Physiological Therapeutics·Christopher J CollocaRobert Gunzburg
May 17, 2003·Journal of Manipulative and Physiological Therapeutics·Christopher J CollocaDaryn E Seltzer
Apr 1, 1997·Clinical Biomechanics·U M KujalaJ J Salminen
May 20, 2005·The Journal of Orthopaedic and Sports Physical Therapy·George J BeneckChristopher M Powers
Mar 25, 2014·The Spine Journal : Official Journal of the North American Spine Society·Seiji OhtoriKazuhisa Takahashi
Jun 2, 2001·Archives of Physical Medicine and Rehabilitation·T JacobL Epstein
Dec 1, 2007·Journal of Applied Physiology·Michele C BattiéJaakko Kaprio
Jan 27, 2018·Spine Surgery and Related Research·Seiji OhtoriGen Inoue

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.