Lumbosacral intraspinal paraganglioma: clinicopathological and computed tomography/magnetic resonance imaging features of 13 cases

World Neurosurgery
Xiaoping YiXiaoyan Long

Abstract

To retrospectively review the clinicopathological features and computed tomography (CT) and magnetic resonance imaging (MRI) findings of lumbosacral intraspinal paragangliomas (PGLs). Thirteen patients with surgically and pathologically confirmed lumbosacral intraspinal PGLs were enrolled. Their clinicopathological data and imaging findings were retrospectively reviewed. Ten male and 3 female patients with a median age of 43 years (range, 36-74 years) were included. CT or MRI revealed a well-defined (n = 13), oval (n = 10), or striated (n = 3) mass with heterogeneous (n = 6) or homogeneous density/signal intensity (n = 7). The lesions appeared isointense (n = 13) and mildly hyperintense (n = 13) on magnetic resonance T1-weighted imaging (T1WI) and T2WI, respectively. On enhanced CT/MRI, markedly heterogeneous (n = 6) and homogeneous (n = 7) enhancement patterns were observed. The "tadpole" sign was observed in 9 cases. Systolic (SBP) and diastolic (DBP) blood pressure were higher before than after surgery (PSBP= 0.002 and PDBP= 0.001). Both SBP and DBP were reduced to normal after surgery. No recurrence or metastatic disease was found during the follow-up period. Lumbosacral intraspinal PGLs should be considered when a mass app...Continue Reading

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