PMID: 11905552Mar 22, 2002Paper

Lung abscess in adults: clinical comparison of immunocompromised to non-immunocompromised patients

Respiratory Medicine
N MansharamaniH Koziel

Abstract

Information related to the clinical characteristics and isolated microbes associated with lung abscesses comparing immunocompromised (IC) to non-immunocompromised (non-IC) patients is limited. A retrospective review for 1984-1996 identified 34 consecutive adult cases of lung abscess (representing 0.2% of all cases of pneumonia), including 10 non-IC and 24 IC patients. Comparison of age, gender, tobacco use, pre-existing pulmonary disease or recognized aspiration risk factors were not significantly different between the two groups. Upper lobe involvement accounted for the majority of cases, although multi-lobe involvement was limited to IC patients. There were no differences in the need for surgical intervention, and mortality was very low for both groups. Anaerobes were the most frequent isolates for non-IC patients (30%), whereas aerobes were the most frequent isolate for IC patients (63%). Importantly, certain organisms were exclusively isolated in the IC group and multiple isolates were obtained only from the IC patients.Thus, comparing non-IC to IC patients, clinical characteristics may be similar whereas important differences may exist in the microbiology associated with lung abscess. These findings have important implicat...Continue Reading

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Citations

Feb 7, 2014·Journal of Medical Case Reports·Dante N SchiavoJay H Ryu
Oct 30, 2012·The Medical Clinics of North America·Himanshu Desai, Aarti Agrawal
Apr 24, 2010·Revue de pneumologie clinique·N PaleironF Grassin
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Apr 19, 2003·Current Opinion in Pulmonary Medicine·Naresh G Mansharamani, Henry Koziel
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Dec 2, 2020·Zentralblatt für Chirurgie·Ludger Hillejan
Jun 9, 2021·Therapeutic Advances in Respiratory Disease·Thomas MaitreGilles Pialoux

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