Lung cancer screening implementation: Complexities and priorities.

Respirology : Official Journal of the Asian Pacific Society of Respirology
Nicole M RankinH M Marshall

Abstract

Lung cancer is the number one cause of cancer death worldwide. The benefits of lung cancer screening to reduce mortality and detect early-stage disease are no longer in any doubt based on the results of two landmark trials using LDCT. Lung cancer screening has been implemented in the US and South Korea and is under consideration by other communities. Successful translation of demonstrated research outcomes into the routine clinical setting requires careful implementation and co-ordinated input from multiple stakeholders. Implementation aspects may be specific to different healthcare settings. Important knowledge gaps remain, which must be addressed in order to optimize screening benefits and minimize screening harms. Lung cancer screening differs from all other cancer screening programmes as lung cancer risk is driven by smoking, a highly stigmatized behaviour. Stigma, along with other factors, can impact smokers' engagement with screening, meaning that smokers are generally 'hard to reach'. This review considers critical points along the patient journey. The first steps include selecting a risk threshold at which to screen, successfully engaging the target population and maximizing screening uptake. We review barriers to smoke...Continue Reading

References

Mar 12, 2004·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Matthew M ClarkStephen J Swensen
Feb 8, 2005·Radiology·Stephen J SwensenKatie L Allen
Jan 27, 2006·The New England Journal of Medicine·Christopher A HaimanLoïc Le Marchand
Nov 30, 2006·Psychology, Health & Medicine·Mitchell G WeissDaryl Somma
Jan 2, 2007·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Kathryn L TaylorEdward Gelmann
May 18, 2007·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Ellen R GritzCheryl G Healton
Mar 14, 2009·The European Respiratory Journal·K A M van den BerghH J de Koning
Jul 4, 2009·The Lancet Oncology·David P WellerAllen J Dietrich
Dec 2, 2010·Journal of the National Cancer Institute·UNKNOWN National Lung Screening Trial Research TeamPaul F Pinsky
Dec 15, 2010·The European Respiratory Journal·C M van der AalstH J de Koning
Feb 18, 2011·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Mie Sara HestbechJohn Brodersen
Jul 1, 2011·The New England Journal of Medicine·UNKNOWN National Lung Screening Trial Research TeamJoRean D Sicks
Sep 6, 2011·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Pamela M McMahonG Scott Gazelle
Nov 8, 2011·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Carlijn M van der AalstRob J van Klaveren
Nov 23, 2011·Thorax·Deesha PatelUNKNOWN Lung-SEARCH Investigators
Mar 31, 2012·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·C M van der AalstH J de Koning
May 23, 2012·BMC Cancer·Suzanne K ChambersDianne L O'Connell
Jun 2, 2012·Journal of Medical Screening·Pamela M MarcusKavita Garg
Jun 12, 2012·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Sirisha JonnalagaddaJuan P Wisnivesky
Feb 22, 2013·The New England Journal of Medicine·Martin C TammemägiChristine D Berg
Apr 30, 2013·Journal of the American College of Radiology : JACR·Brady J McKeeChristoph Wald
May 24, 2013·The New England Journal of Medicine·Timothy R ChurchSarah Baum
Jun 15, 2013·Chest·Nichole T TannerGerard A Silvestri
Jul 19, 2013·The New England Journal of Medicine·Stephanie A KovalchikHormuzd A Katki
Sep 4, 2013·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Elyse R ParkMark Nichter
Sep 6, 2013·The New England Journal of Medicine·Annette McWilliamsStephen Lam
Sep 6, 2013·The New England Journal of Medicine·Denise R AberleUNKNOWN National Lung Screening Trial Research Team
Dec 25, 2013·Journal of Urban Health : Bulletin of the New York Academy of Medicine·Gopal K Singh, Mohammad Siahpush
Jan 1, 2014·Annals of Internal Medicine·Virginia A Moyer, UNKNOWN U.S. Preventive Services Task Force
Mar 29, 2014·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Jennifer DelmericoK Michael Cummings
Apr 29, 2014·Oncology Nursing Forum·Lisa Carter-HarrisSusan M Rawl
May 29, 2014·BMJ : British Medical Journal·Martin C Tammemagi, Stephen Lam
May 30, 2014·Journal of the National Cancer Institute·Martin C TammemägiKathryn L Taylor
Jun 13, 2014·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Giulia VeronesiMassimo Bellomi
Aug 12, 2014·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Sonya CressmanUNKNOWN Pan-Canadian Early Detection of Lung Cancer Study Team

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Citations

Oct 30, 2020·Respirology : Official Journal of the Asian Pacific Society of Respirology·Alistair Miller, Emily Stone
Aug 1, 2021·Nanoscale Research Letters·Xin HuangBingdi Chen

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