Lung cancer with chest wall involvement: predictive factors of long-term survival after surgical resection

Lung Cancer : Journal of the International Association for the Study of Lung Cancer
Luca VoltoliniGiuseppe Gotti

Abstract

Multimodal management of lung cancer extending to chest wall and type of surgical procedure to be performed are still debated. The aim of this retrospective analysis was to analyze the predictive factors of long-term survival after surgery, focusing on depth of infiltration, type of surgical intervention and possible role of preoperative therapies, comparing survival of these patients with that of a group of patients affected by a Pancoast tumour and surgical treated in the same period. We reviewed records of 83 consecutive patients with NSCLC in stage T3 (owing to direct extension to chest wall), who underwent surgical resection in our Thoracic Surgery Unit between January 1994 and December 2003. Patients were classified in two groups: pancoast tumours (PT) or chest wall extending tumours (CW): survival and prognostic factors of each category were analyzed. In the CW group we had 68 patients: 45 were in stage IIB (pT3N0), 23 in stage IIIA (pT3-N1-2). Histology revealed adenocarcinoma in 23 cases, squamous cell carcinoma in 34, large cells anaplastic carcinoma in 8, adenosquamous carcinoma in 3. An involvement of chest wall tissues beyond the endothoracic fascia was found in 21 patients, while in the remaining 47 the invasion o...Continue Reading

References

Jul 27, 1999·The Annals of Thoracic Surgery·R J DowneyR J Ginsberg
Oct 29, 2000·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·A ChapelierP Dartevelle
Mar 30, 2001·The Journal of Thoracic and Cardiovascular Surgery·F FaccioloM Martelli

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Citations

Apr 10, 2008·Chest·Momen M Wahidi
Feb 9, 2011·Archivos de bronconeumología·Ignacio MuguruzaMariano García-Yuste
May 20, 2009·Archivos de bronconeumología·Gregorio Gallardo-ValeraJesús Loscertales
Oct 5, 2007·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·I KappersH M Klomp
Apr 2, 2017·Thoracic Surgery Clinics·Michael Lanuti
Sep 1, 2017·Journal of Plastic Surgery and Hand Surgery·Hiroaki KuwaharaErkki Tukiainen
Jul 26, 2021·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Mengmeng ZhaoChang Chen

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