Lung function and anxiety in association with dyspnoea: the HUNT study

Respiratory Medicine
Linda LeivsethA Langhammer

Abstract

Few studies from the general population have investigated the role of anxiety in reporting dyspnoea. We examined the independent and combined association of lung function and anxiety symptoms with the prevalence of dyspnoea in different situations. The study included 5627 women and 5066 men who participated in the Lung study of the Nord-Trøndelag Health Study second survey in 1995-97. In a cross-sectional design we used logistic regression to calculate adjusted odds ratios (ORs) for reporting dyspnoea associated with levels of percent predicted FEV(1) (ppFEV(1)) and anxiety (Hospital Anxiety and Depression Scale). Overall, there was a linear inverse association between ppFEV(1) and dyspnoea (all P(trend) < 0.001), and a positive association between anxiety symptoms and dyspnoea (all P(trend) < 0.001). In combined analysis, using people with ppFEV(1) ≥100 without anxiety as reference, the OR (95% confidence interval) for reporting dyspnoea when walking on flat ground was 6.23 (3.45-11.28) in women with ppFEV(1) <80 without anxiety and 15.14 (7.13-32.12) in women with ppFEV(1) <80 with anxiety. The corresponding ORs among men were 5.75 (2.23-14.18) and 15.19 (4.74-48.64), respectively. Similar patterns were seen for dyspnoea when...Continue Reading

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Citations

Mar 8, 2013·Depression and Anxiety·Martin P Paulus
Aug 26, 2014·Journal of Pain and Symptom Management·Mireille Michel-CherquiMarc Fischler
Jun 30, 2018·BMJ Open Respiratory Research·Alice MalpassJames W Dodd
Nov 1, 2017·International Journal of Palliative Nursing·Josephine Pople
Oct 25, 2016·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Yu KeAlexandre Chan

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