Jun 1, 1989

Lung metastases of prostatic cancer vanished by early combined hormonal and chemotherapy: report of a case

Hinyokika kiyo. Acta urologica Japonica
S SakamotoK Okada


A 69-year-old man initially came to our hospital with the chief complaint of dysuria and hematuria. On rectal examination, the prostate gland was found to be grossly enlarged and rock hard in consistency. Abnormal laboratory data included: lactate dehydrogenase, alkaline phosphatase, acid phosphatase and prostatic acid phosphatase. Chest X-ray revealed multiple nodular lesions in both lung fields. Pathologic findings of the prostate needle biopsy revealed moderately well differentiated adenocarcinoma. Early combined hormonal and chemotherapy (adriamycin, TGF, methotrexate, bleomycin) was performed. After two courses of this regimen, the pulmonary lesions vanished completely. In addition, partial disappearance of osteoblastic lesions on bone scans was recognized.

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Mentioned in this Paper

Prostatic Neoplasms
Acid Phosphatase
Alkaline Phosphatase Measurement
Alkaline Phosphatase

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