Lung resection in the pulmonary-compromised patient

Thoracic Surgery Clinics
Jocelyne Martin

Abstract

Every patient evaluated for lung resection should have preoperative pulmonary function testing. Patients with a significant decrease in FEV1% (approximately 60%-70% or less) should have a quantitative radionuclide perfusion scanning. Patients with a low ppoFEV1% (approximately 40%) should be considered for exercise testing because their risk for developing postoperative complications is higher. A VO2max between 10 to 15 ml/kg/minute or a ppoVO2max of less than 10 ml/kg/minute would usually be considered prohibitive for surgery. Nevertheless, no single criterion should be used to exclude a patient from surgery. Rather, the use of multiple preoperative studies is needed to select patients who will tolerate and benefit from pulmonary resection. Surgical interventions other than standard lobectomies or pneumonectomies can be offered to selected high-risk patients. Experience from lung volume reduction surgery has shown that some patients who would have been considered inoperable can safely undergo resection of their lung cancer.

References

May 15, 1990·Annals of Internal Medicine·J D ZibrakK Marton
Feb 2, 1970·JAMA : the Journal of the American Medical Association·M Stein, E L Cassara
Apr 1, 1984·The Annals of Thoracic Surgery·L P FaberC F Kittle
Feb 1, 1995·The Journal of Thoracic and Cardiovascular Surgery·M K FergusonR Mick
Oct 1, 1994·American Journal of Respiratory and Critical Care Medicine·R J PierceC E Barter
May 1, 1996·The Journal of Thoracic and Cardiovascular Surgery·H A GaissertJ C Wain
Jun 1, 1997·Hematology/oncology Clinics of North America·T L Petty
Aug 1, 1997·The Annals of Thoracic Surgery·M NinanR J Keenan
Apr 16, 1998·The Journal of Thoracic and Cardiovascular Surgery·S R DeMeesterJ D Cooper
May 16, 1998·The European Respiratory Journal·C T Bolliger, A P Perruchoud
Jan 7, 1999·The European Respiratory Journal·J RibasR Rodriguez-Roisin
May 6, 1999·American Journal of Respiratory and Critical Care Medicine·C WyserC T Bolliger
Jun 4, 1999·The Annals of Thoracic Surgery·J WangM K Ferguson
May 18, 2000·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·F TroncJ Deslauriers
Jun 12, 2002·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Yasuo SekineTakehiko Fujisawa
Jan 16, 2003·Chest·Michael A BecklesUNKNOWN American College of Chest Physicians

❮ Previous
Next ❯

Citations

Feb 10, 2006·Cancer Investigation·Katherine E Posther, David H Harpole

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2021 Meta ULC. All rights reserved