Lung transplant referral practice patterns: a survey of cystic fibrosis physicians and general pulmonologists.

BMC Pulmonary Medicine
Bethany L BartleyLael M Yonker

Abstract

Many individuals with cystic fibrosis (CF) die from respiratory failure without referral for lung transplant. Physician practices that may expedite, delay, or preclude referral, are poorly understood. Two parallel, web-based surveys focusing on lung transplant referral triggers and barriers, as well as pre-referral evaluation, were emailed to pulmonologists practicing in the New England region. One questionnaire was sent to CF providers (n = 61), and the second to general pulmonary providers practicing at the same institutions (n = 61). There were 43 (70%) responses to the CF provider survey, and 25 (41%) responses to the general pulmonary ('non-CF') provider survey. Primary reasons for CF providers to refer their patients included: rapidly declining lung function (91%) and a forced expiratory volume in 1 s (FEV1) below 30% predicted (74%). The greatest barriers to referral for both CF and non-CF providers included active tobacco use (65 and 96%, respectively, would not refer), and active alcohol or other substance use or dependence (63 and 80%). Furthermore, up to 42% of CF providers would potentially delay their referral if triple-combination therapy or other promising new, disease-specific therapy were anticipated. In genera...Continue Reading

References

Apr 30, 1992·The New England Journal of Medicine·E KeremH Levison
Sep 6, 2000·Pediatric Pulmonology·W Robinson, D A Waltz
Oct 31, 2002·American Journal of Respiratory and Critical Care Medicine·Nicole Mayer-HamblettMoira L Aitken
Oct 28, 2008·Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society·Gregory S SawickiWalter M Robinson
Apr 18, 2013·American Journal of Respiratory and Critical Care Medicine·Gabriel ThabutDimitris Rizopoulos
Aug 3, 2014·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·David WeillAllan R Glanville
Sep 24, 2015·Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society·Clémence MartinPierre-Régis Burgel
Feb 10, 2016·Clinics in Chest Medicine·Matthew R Morrell, Joseph M Pilewski
Sep 24, 2016·Pediatric Pulmonology·Beth A SmithAlexandra L Quittner
May 2, 2018·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Mary Amanda DewPaula C Zimbrean
Oct 20, 2018·The New England Journal of Medicine·Dominic KeatingUNKNOWN VX16-445-001 Study Group
Mar 31, 2019·Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society·Kathleen J RamosUNKNOWN CF Lung Transplant Referral Guidelines Committee
Apr 21, 2019·Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society·Kathleen J RamosMoira L Aitken
Sep 25, 2019·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Don HayesUNKNOWN International Society for Heart and Lung Transplantation
Sep 25, 2019·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Daniel C ChambersUNKNOWN International Society for Heart and Lung Transplantation

❮ Previous
Next ❯

Software Mentioned

SurveyGizmo©
SPSS Statistics

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.