Lung Transplantation and the Era of the Sensitized Patient.

Frontiers in Immunology
Katherine A YoungL D Snyder

Abstract

Long term outcomes in lung transplant are limited by the development of chronic lung allograft dysfunction (CLAD). Within the past several decades, antibody-mediated rejection (AMR) has been recognized as a risk factor for CLAD. The presence of HLA antibodies in lung transplant candidates, "sensitized patients" may predispose patients to AMR, CLAD, and higher mortality after transplant. This review will discuss issues surrounding the sensitized patient, including mechanisms of sensitization, implications within lung transplant, and management strategies.

References

Feb 14, 2004·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·William M BaldwinE Rene Rodriguez
Jul 5, 2005·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Denis HadjiliadisShaf Keshavjee
Apr 15, 2006·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·T M EganF L Grover
May 24, 2008·The Annals of Thoracic Surgery·Ashish S ShahJohn V Conte
Jul 19, 2008·The New England Journal of Medicine·Ashley A VoStanley C Jordan
Apr 27, 2010·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·F VincentiC P Larsen
Apr 27, 2010·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·A DurrbachJ Grinyó
Jun 19, 2010·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Ramsey R HachemElbert P Trulock
Sep 25, 2012·Current Respiratory Care Reports·Ramsey Hachem
Dec 25, 2012·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Leonard J LoboIsabel P Neuringer
Aug 21, 2013·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Chad A WittRamsey R Hachem
Mar 29, 2014·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·L D SnyderS M Palmer
Apr 23, 2014·American Journal of Respiratory and Critical Care Medicine·Miae KimHilary J Goldberg
Jun 24, 2014·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·John D SmithMartin Carby
Dec 3, 2014·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Matthew R MorrellAdriana Zeevi
Jan 24, 2015·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·K J TinckamL G Singer
Jul 15, 2015·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·James P BosanquetRamsey R Hachem
Mar 12, 2016·American Journal of Respiratory and Critical Care Medicine·Jussi M TikkanenKathryn Tinckam
Apr 6, 2016·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Deborah J LevineAdriana Zeevi
Sep 22, 2017·Journal of Thoracic Disease·Jens Gottlieb
Oct 11, 2017·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·P R AguilarR R Hachem
Mar 25, 2018·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·R A BrayC P Larsen
Dec 19, 2018·The Journal of Clinical Investigation·Wenjun LiDaniel Kreisel
Feb 15, 2019·Annals of the American Thoracic Society·Laneshia K TagueRamsey R Hachem
Mar 31, 2019·Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society·Kathleen J RamosUNKNOWN CF Lung Transplant Referral Guidelines Committee
Apr 10, 2019·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Geert M VerledenRobin Vos
Aug 28, 2019·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Ronald F ParsonsHoward M Gebel
Oct 22, 2019·Journal of Thoracic Disease·Omar Shweish, Goutham Dronavalli
Oct 22, 2019·Journal of Thoracic Disease·Amit D Parulekar, Christina C Kao
Mar 12, 2020·Current Transplantation Reports·Ronald F ParsonsI Raul Badell
May 2, 2020·Annals of Translational Medicine·Henry W Ainge-Allen, Allan R Glanville
May 2, 2020·Annals of Translational Medicine·Amit I Bery, Ramsey R Hachem
May 30, 2020·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·M AversaL G Singer
Jun 9, 2020·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Shudhanshu AlishettiMarlena V Habal
Jul 24, 2020·European Respiratory Review : an Official Journal of the European Respiratory Society·Sophie C van der MarkMerel E Hellemons

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