PMID: 9536502Apr 16, 1998Paper

Lung transplantation at the University of Lund 1990-1995. Analysis of the first 39 consecutive patients

Scandinavian Cardiovascular Journal : SCJ
L ErikssonJ O Solem

Abstract

Between 1990 and 1995 39 patients were lung transplanted at the University Hospital in Lund. This is a retrospective review of survival and lung function in these patients. There were 17 single-lung transplants (SLT), 21 double-lung transplants (DLT) and 1 heart-lung transplant (HLT). Seven patients died during the period, giving an overall survival of 82%. One-year survival according to Kaplan-Meier survival analysis was 87%, and 2-year survival was 83%. Vital capacity and forced expiratory volume in 1 s (FEV1) 1 year after transplantation were 91% and 100% of predicted, respectively, in the DLT group and 60% and 50% in the SLT group. Bronchiolitis obliterans syndrome (BOS) developed in 11 of the 35 patients (31%) surviving more than 6 months, 2/21 in the DLT group and 8/13 in the SLT group and in the patient with HLT. The median time until detection of BOS was 11 months after the operation (range 6-18 months). Working capacity 1 year after transplantation was 60% of predicted in the DLT group and 47% of predicted in the SLT group. Ventilatory capacity was no longer function limiting. Lung transplantation today is a therapeutic option with a good medium-term survival and good functional results in selected patients with severe...Continue Reading

References

Jan 1, 1989·The Annals of Thoracic Surgery·J D Cooper
May 1, 1986·The New England Journal of Medicine·UNKNOWN Toronto Lung Transplant Group
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Dec 21, 1963·JAMA : the Journal of the American Medical Association·J D HARDYG R WALKER

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Citations

Aug 12, 2000·Acta Anaesthesiologica Scandinavica·H J Toivonen
Jun 1, 2011·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Annika Andersson-SjölandGunilla Westergren-Thorsson

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