Lung Transplantation in Idiopathic Pulmonary Fibrosis

Medical Sciences : Open Access Journal
Rosalía Laporta HernandezPiedad Ussetti Gil

Abstract

Despite the advances in recent years in the treatment of idiopathic pulmonary fibrosis (IPF), it continues to be a progressive disease with poor prognosis. In selected patients, lung transplantation may be a treatment option, with optimal results in survival and quality of life. Currently, pulmonary fibrosis is the main cause of lung transplantation. However, mortality on the waiting list of these patients is high, since many patients are referred to the transplant units with advanced disease. There is not a parameter that can predict the survival of a specific patient. Different variables are to be considered in order to decide the right time to send them to a transplant unit. It is also very difficult to decide when to include these patients on the waiting list. Every patient diagnosed with IPF, without contraindications for surgery, should be referred early to a transplant unit for assessment. A uni or bilateral transplantation will be decided based on the characteristics of the patient and the experience of each center. The post-transplant survival of recipients with IPF is lower than that observed in other diseases, such as cystic fibrosis or chronic obstructive pulmonary disease as a consequence of their older age and the...Continue Reading

References

Mar 21, 2001·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·S J ParkR M Bolman
Jul 4, 2001·American Journal of Respiratory and Critical Care Medicine·N MogulkocUNKNOWN Greater Manchester Pulmonary Fibrosis Consortium
Oct 6, 2001·American Journal of Respiratory and Critical Care Medicine·T E KingR M Cherniack
May 30, 2003·American Journal of Respiratory and Critical Care Medicine·Harold R CollardKevin K Brown
Aug 21, 2003·The Journal of Thoracic and Cardiovascular Surgery·Gabriel ThabutMichel Fournier
Sep 7, 2005·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·T P M WhelanP S Dahlberg
Jan 3, 2006·American Journal of Respiratory and Critical Care Medicine·Richard A BelkinGreta R Bunin
Jan 3, 2006·The European Respiratory Journal·G RaghuC A Pellegrini
Jan 10, 2006·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Kendra J McAnallyDavid E Taylor
Jul 19, 2008·American Journal of Respiratory and Critical Care Medicine·Jennifer T CronkhiteChristine Kim Garcia
Aug 30, 2008·American Journal of Respiratory and Critical Care Medicine·Richard B HubbardAndrew W Fogarty
Jul 28, 2009·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Christian A MerloAshish S Shah
Apr 1, 2010·Seminars in Respiratory and Critical Care Medicine·S Samuel WeigtJohn A Belperio
Jul 6, 2010·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Steven D NathanErik Edwards
Oct 12, 2010·American Journal of Respiratory and Critical Care Medicine·Brett LeyTalmadge E King
Feb 1, 2011·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Stijn E VerledenBart M Vanaudenaerde
Mar 23, 2011·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Masaaki SatoShaf Keshavjee
Apr 8, 2011·American Journal of Respiratory and Critical Care Medicine·Ganesh RaghuUNKNOWN ATS/ERS/JRS/ALAT Committee on Idiopathic Pulmonary Fibrosis
Aug 13, 2011·Transplantation·Geert M VerledenBart M Vanaudenaerde
Sep 4, 2012·Archivos de bronconeumología·Elisabeth CollAntonio Román
Jan 9, 2013·Respirology : Official Journal of the Asian Pacific Society of Respirology·Oren FruchterMordechai R Kramer
Jan 30, 2013·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·V E KennedyS M Palmer
Mar 5, 2013·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Franziska IhleClaus Neurohr
Mar 9, 2013·The European Respiratory Journal·Edoardo SavarinoVincenzo Savarino
Sep 14, 2013·Medicina clínica·Cristina BerasteguiAntonio Roman
May 17, 2014·The European Respiratory Journal·Leann L SilhanMary Armanios
Jul 25, 2014·Current Opinion in Pulmonary Medicine·Jens Gottlieb
Aug 3, 2014·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·David WeillAllan R Glanville
Aug 17, 2014·BMC Pulmonary Medicine·Kristin D KistlerDirk Esser
Sep 23, 2014·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Roger D YusenUNKNOWN International Society for Heart and Lung Transplantation
Nov 29, 2014·Thoracic Surgery Clinics·Varun PuriBryan F Meyers
Jan 24, 2015·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Raphael BorieUNKNOWN Groupe d’Etudes et de Recherche sur les Maladies “Orphelines” Pulmonaires (GERM“O”P)
Jun 16, 2015·Respirology : Official Journal of the Asian Pacific Society of Respirology·Jinghong DaiLong Yi
Jul 16, 2015·American Journal of Respiratory and Critical Care Medicine·Ganesh RaghuUNKNOWN Latin American Thoracic Association
Jul 27, 2015·The Annals of Thoracic Surgery·Brian C GulackMatthew G Hartwig
Sep 24, 2015·Jornal brasileiro de pneumologia : publicaça̋o oficial da Sociedade Brasileira de Pneumologia e Tisilogia·Adalberto Sperb RubinJosé Jesus Camargo
Dec 5, 2015·Respirology : Official Journal of the Asian Pacific Society of Respirology·A Whitney BrownSteven D Nathan
Mar 22, 2016·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Hendrik SuhlingJens Gottlieb
Oct 16, 2016·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·J P SingerP D Blanc

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