Lung Ultrasound as a Screening Method for Interstitial Lung Disease in Patients With Systemic Sclerosis

Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases
Romina Isabel HassanMaria Del Carmen Binda

Abstract

Patients with systemic sclerosis (SSc) undergo chest radiographs and high-resolution computed tomography (HRCT) of the thorax both for interstitial lung disease (ILD) detection and for disease progression monitoring. The aim of this study was to assess whether lung ultrasound (LUS) is a useful screening tool for ILD in patients with SSc in comparison with HRCT. This was a longitudinal cohort study carried out from December 2015 to April 2016. An LUS was performed to examine B-lines in 67 consecutive patients who met the 2013 American College of Rheumatology/European League Against Rheumatism classification criteria for SSc and had a previous HRCT. B-lines were quantified and classified according to the score modified from Picano. Severity and extent of lung involvement on the HRCT were determined by means of the Warrick score. Twenty-nine patients had both abnormal HRCT (Warrick score >7) and abnormal LUS, 2 had a mild score (6-15 B-lines), and 27 had either moderate or severe scores (≥16 B-lines). Of the 38 patients with negative HRCT, 25 presented some degree of lung involvement on the LUS. Thus, LUS has a sensitivity of 100% and a specificity of 34%. Receiver operating characteristic curve analysis showed the analytic relati...Continue Reading

References

Dec 31, 1997·American Journal of Respiratory and Critical Care Medicine·D LichtensteinO Barré
Feb 28, 2006·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Eugenio PicanoGaetano Mottola
Mar 7, 2012·Intensive Care Medicine·Giovanni VolpicelliUNKNOWN International Liaison Committee on Lung Ultrasound (ILC-LUS) for International Consensus Conference on Lung Ultrasound (ICC-
May 17, 2012·Annals of the Rheumatic Diseases·Tatiana BarskovaMarco Matucci Cerinic

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Citations

Sep 6, 2020·Current Opinion in Rheumatology·Anna-Maria Hoffmann-Vold, Øyvind Molberg
Aug 14, 2020·Current Rheumatology Reports·Molly Wolf, Sydney B Montesi
Jun 24, 2021·Clinical Rheumatology·Esther F Vicente-RabanedaIngrid Möller
Aug 8, 2021·Journal of Clinical Medicine·Natalia BudaMarcin Wełnicki
Sep 3, 2021·Therapeutic Advances in Musculoskeletal Disease·Panagiotis PanagopoulosAthanasios Tzioufas

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