PMID: 6966666Jun 1, 1980Paper

Lupus band test in untreated SLE patients: correlation of immunoglobulin deposition in the skin of the extensor forearm with clinical renal disease and serological abnormalities

The Journal of Investigative Dermatology
T T ProvostM Reichlin

Abstract

This study demonstrated that 88% of untreated systemic lupus erythematosus patients with clinical renal disease displayed the deposition of immunoglobulin and complement at the dermal epidermal junction of the noninvolved light exposed extensor surface of the upper 1/3 of the forearm (P less than 0.005) (positive lupus band test). Eighty-five percent of these untreated systemic lupus erythematosus patients with anti-deoxyribonucleic acid antibodies (native and/or single stranded) (P less than 0.001) and 96% of systemic lupus erythematosus patients with hypocomplementemia had a positive lupus band test (P less than 0.001). Those systemic lupus erythematosus patients with a negative lupus band test or a positive lupus band test composed of pure IgM had a decreased incidence of renal disease, serum hypocomplementemia and anti-DNA antibodies. Their sera, however, frequently contained antibodies directed against nuclear ribonuclear protein or against the cytoplasmic non-nucleic acid glycoprotein termed Ro. On the contrary, 85% of systemic lupus erythematosus patients with a positive lupus band test composed solely or in part of IgG, had anti-DNA antibodies (P less than 0.001). Their sera also frequently contained anti-Sm antibodies....Continue Reading

Citations

Dec 1, 1983·Journal of Cutaneous Pathology·E M McMillan
Sep 1, 1982·Clinical and Experimental Dermatology·A R Ahmed, E Drenick
Feb 13, 2001·Journal of Cutaneous Pathology·A N Crowson, C Magro
Jan 1, 1983·Acta Medica Scandinavica·R JonssonN G Westberg
Sep 1, 1981·International Journal of Dermatology·T T Provost
Jun 1, 1982·Arthritis and Rheumatism·K B KulickM Reichlin
May 1, 1984·Clinical and Experimental Dermatology·N R Rowell
Feb 1, 1985·Journal of Cutaneous Pathology·Z ChenS K Ainsworth
Sep 24, 2005·Rheumatology International·M A A DancourE Bouskela
Apr 1, 1984·Arthritis and Rheumatism·C D SmithN F Rothfield
Jul 1, 1983·Clinical and Experimental Dermatology·A R Ahmed, S Workman
May 15, 2003·Arthritis and Rheumatism·Cecile GrootscholtenUNKNOWN Dutch Working Party on Systemic Lupus Erythematosus
Jan 1, 1983·International Journal of Dermatology·J E BernsteinA J Aronson
Aug 14, 1999·The American Journal of Dermatopathology·H Ruiz, J L Sánchez
Jul 1, 1988·Journal of Clinical Immunology·T T Provost, M Reichlin
Jun 1, 1982·International Journal of Dermatology·R C Ongley
Aug 6, 1983·British Medical Journal·M L Snaith
Jan 1, 1981·Springer Seminars in Immunopathology·E L Alexander, T T Provost
Aug 1, 1996·Journal of the American Academy of Dermatology·T T ProvostE Simmons-O'Brien
Apr 1, 1983·Human Pathology·E R Farmer, T T Provost

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