Lupus nephritis

Seminars in Nephrology
Neerja AgrawalIan R Rifkin

Abstract

Lupus nephritis is one of the more serious manifestations of the systemic autoimmune disease, systemic lupus erythematosus, and is associated with considerable morbidity and even mortality. Treatment remains problematic, particularly in terms of controlling the underlying disease process while at the same time preventing unacceptable side effects of therapy. In recent years, clinical trials have started to define optimum regimens of the immunosuppressive agents presently in use. The etiology and pathogenesis of systemic lupus erythematosus and lupus nephritis still are understood incompletely. Nevertheless, insights gained from basic science research in both animals and human beings now are being translated into newer therapies that have the potential to be safer and more specific than those currently available.

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Citations

Nov 27, 2010·Irish Journal of Medical Science·G-C WuH-F Pan
May 18, 2011·Arthritis Care & Research·Katherine A SlawskyThomas F Goss
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May 20, 2017·QJM : Monthly Journal of the Association of Physicians·E ChalayerP Cathébras

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