Lupus vulgaris occurring in a locus minoris resistentiae

Journal of Cutaneous Medicine and Surgery
Richard LongNorman Wasel

Abstract

The pathogenesis of lupus vulgaris, a form of cutaneous tuberculosis, is not always clear, especially in patients who do not have coexistent extracutaneous tuberculosis and in patients with single lesions. To report a case of lupus vulgaris in a locus minoris resistentiae (a site of reduced resistance) and to use a unique set of clinical circumstances and laboratory tests to reconstruct the pathogenesis of the lesion and the response to treatment. Lupus vulgaris can occur in a locus minoris resistentiae; local trauma and possibly other factors, such as increased temperature, topical corticosteroids, and the virulence of the infecting strain, may facilitate the growth of Mycobacterium tuberculosis present at a locus minoris resistentiae as a result of a silent bacillemia.

References

Jul 1, 1990·International Journal of Dermatology·A S Boyd, K H Neldner
Apr 1, 1971·Annals of Internal Medicine·W W Stead, J H Bates
Jul 8, 2005·Journal of Clinical Microbiology·Anthony G TsolakiPeter M Small

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BETA
biopsy

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