PMID: 109032Jan 1, 1979

Luteal insufficiency and benign breast diseases. Study in the light of data from the combined LH-RH + TRH test together with the study of ovarian steroids

Annales d'endocrinologie
S GellerR Scholler


Luteal deficiency has been attributed a patho-physiologic role in benign fibro-cystic breast disease, whereas Prolactin would not be involved in this disease. To tes these hypotheses, patients with fibro-cystic breast disease have been investigated through the combined LH-RH + TRH test, coupled with ovarian steroids estimations. 63 menstruating patients with ovulatory cycles, as evidenced by the temperature curve and proven fibro-cystic breast disease, as demonstrated by senography and thermogrphy and/or operation, have been selected for this study. The findings do not favour the role of luteal dificiency but rather the role of PRL hyperactivity in the pathol-physiology of fibro-cySTIC BREAST DISEASE.

Related Concepts

Endocrine Breast Diseases
Estrogen Effect
Follicle Stimulating Hormone
Gonadorelin Hydrochloride
Progesterone, (17 alpha)-Isomer
Proterelin Tartrate Hydrate

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