Luteinized unruptured follicle syndrome: incidence and recurrence rate in infertile women with unexplained infertility undergoing intrauterine insemination

Human Reproduction
H QublanM Balawneh

Abstract

The objective of this study was to determine the incidence and recurrence rate of luteinized unruptured follicle (LUF) syndrome in women with unexplained infertility undergoing intrauterine insemination (IUI). A total of 167 women with unexplained infertility who underwent 292 cycles of IUI were enrolled in the study. All patients were treated with clomiphene citrate, 50-150 mg/daily from day 5 to 9 of their menstrual cycle. Ultrasound examination to confirm ovulation was performed on the day of IUI (day 0) and every day thereafter for another 3 days (days 1, 2 and 3). A total of 69 women who failed to conceive in the first cycle and 56 women who failed to conceive in the second cycle underwent second and third cycles, respectively. Of the total 167 patients who underwent first cycle, 42 (25%) had LUF. The incidence of LUF was 56.5% in 69 patients who underwent a second cycle of IUI treatment, of whom 33 patients had LUF in the first cycle with recurrence rate of 78.6%. In 56 patients who underwent 3 consecutive cycles, the incidence of LUF was 58.9% and recurrence rate of 90%. No pregnancies were recorded in patients with LUF during the study period. The incidence and recurrence rate of LUF are significantly increased in subse...Continue Reading

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Citations

Sep 3, 2008·Journal of Assisted Reproduction and Genetics·Tansu Kucuk
Sep 21, 2011·Reproduction : the Official Journal of the Society for the Study of Fertility·R van de LagemaatC M Timmers
Feb 16, 2016·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Mahmoud F Fathalla
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Jun 19, 2012·Clinical Endocrinology·Barbara Sonntag, Michael Ludwig
Nov 20, 2010·American Journal of Reproductive Immunology : AJRI·Kotaro Kitaya, Hisao Yamada
Nov 1, 2015·Translational Research : the Journal of Laboratory and Clinical Medicine·Takeo ShibataTakafumi Utsunomiya
Jun 27, 2015·Steroids·R LeivaR Ecochard
Feb 16, 2015·Journal of Assisted Reproduction and Genetics·Lisa Marii CookinghamMario Ascoli
Dec 18, 2010·Molecular and Cellular Endocrinology·Katharina Spanel-Borowski
Nov 1, 2016·Reproduction : the Official Journal of the Society for the Study of Fertility·Laura T PelegrinaMyriam Raquel Laconi
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Aug 28, 2021·Animals : an Open Access Journal From MDPI·Achraf BenammarPascale Chavatte-Palmer

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