LuxR-type quorum-sensing regulators that are detached from common scents.

Molecular Microbiology
Ching-Sung Tsai, Stephen C Winans

Abstract

The ability of LuxR-type proteins to regulate transcription is controlled by bacterial pheromones, N-acylhomoserine lactones (AHLs). Most LuxR-family proteins require their cognate AHLs for activity, and at least some of them require AHLs for folding and protease resistance. However, a few members of this family are able to fold, dimerize, bind DNA, and regulate transcription in the absence of AHLs; moreover, these proteins are antagonized by their cognate AHLs. Complexes between some of these proteins and their DNA binding sites are disrupted by AHLs in vitro. All such proteins are fairly closely related within the larger LuxR family, indicating that they share a relatively recent common ancestor. The 3' ends of the genes encoding these receptors invariably overlap with the 3' ends of the cognate AHL synthase genes, suggesting additional antagonism at the level of mRNA synthesis, stability or translation.

References

Dec 15, 1991·Proceedings of the National Academy of Sciences of the United States of America·S H Choi, E P Greenberg
Aug 1, 1989·Proceedings of the National Academy of Sciences of the United States of America·J H DevineT O Baldwin
Jul 1, 1984·Proceedings of the National Academy of Sciences of the United States of America·J Engebrecht, M Silverman
Apr 28, 1981·Biochemistry·A EberhardN J Oppenheimer
May 24, 1994·Proceedings of the National Academy of Sciences of the United States of America·I HwangS K Farrand
Jan 1, 1997·Annual Review of Microbiology·G M Dunny, B A Leonard
Jun 24, 1998·Proceedings of the National Academy of Sciences of the United States of America·S B von BodmanD L Coplin
Apr 29, 1999·Proceedings of the National Academy of Sciences of the United States of America·J Zhu, S C Winans
Aug 4, 1999·Proceedings of the National Academy of Sciences of the United States of America·Z Q Luo, S K Farrand
Nov 5, 1999·Methods in Enzymology·M R Parsek, E P Greenberg
Nov 26, 1999·Proceedings of the National Academy of Sciences of the United States of America·M WhiteleyE P Greenberg
Jan 14, 2000·Journal of Bacteriology·K A Egland, E P Greenberg
Apr 8, 2000·Molecular Plant-microbe Interactions : MPMI·R A AnderssonE T Palva
Aug 19, 2000·Infection and Immunity·T R de Kievit, B H Iglewski
Feb 15, 2001·Proceedings of the National Academy of Sciences of the United States of America·J Zhu, S C Winans
Aug 29, 2001·FEMS Microbiology Reviews·N A WhiteheadG P Salmond
Oct 6, 2001·Peptides·M Perego, J A Brannigan
Aug 29, 2002·The EMBO Journal·Alessandro VanniniStefania Di Marco
Mar 20, 2003·Journal of Bacteriology·Victoria E WagnerBarbara H Iglewski
Mar 27, 2003·Molecular Microbiology·Keith F Chater, Sueharu Horinouchi
Jul 26, 2003·The EMBO Journal·Morten HentzerMichael Givskov

❮ Previous
Next ❯

Citations

Jun 1, 2011·World Journal of Microbiology & Biotechnology·Saeed Tarighi, Parissa Taheri
Mar 6, 2012·Journal of Bacteriology·Ann M StevensKendra P Rumbaugh
Jul 17, 2012·Journal of Bacteriology·Verónica I Martínez-SantosJosé L Puente
Jan 1, 2012·ISRN Microbiology·Zsolt GelencsérSándor Pongor
Jan 10, 2014·International Journal of Molecular Sciences·Jindong ZanRussell T Hill
Feb 26, 2016·Frontiers in Cellular and Infection Microbiology·Xin-Yue ChanKok-Gan Chan
Jun 17, 2011·Journal of Cellular Biochemistry·Jing Chen, Jianping Xie
Jun 12, 2014·The FEBS Journal·Karolina MichalskaAndrzej Joachimiak
Sep 4, 2015·Molecular Oral Microbiology·Marie-Claire BoutrinHansel M Fletcher
Feb 24, 2015·Genome Announcements·Nur Izzati MohamadKok-Gan Chan
Nov 1, 2017·American Journal of Respiratory and Critical Care Medicine·Colleen S CurranParizad Torabi-Parizi
Jul 4, 2013·International Journal of Molecular Sciences·Kumari Sonal ChoudharySándor Pongor
May 16, 2015·Natural Product Reports·Stefan Schulz, Susann Hötling
May 24, 2018·MBio·Rhea G AbisadoJosephine R Chandler
Dec 15, 2010·Chembiochem : a European Journal of Chemical Biology·Andrew G PalmerHelen E Blackwell
Feb 20, 2015·Microbiology and Molecular Biology Reviews : MMBR·Burkhard A Hense, Martin Schuster
Aug 23, 2019·Natural Product Reports·Sebastian Götze, Pierre Stallforth
Oct 29, 2013·Molecular BioSystems·Jesper Ferkinghoff-Borg, Thomas Sams
Nov 28, 2013·Chembiochem : a European Journal of Chemical Biology·Christine E McInnis, Helen E Blackwell
Nov 22, 2018·Nature Communications·Jin XuNian Wang

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bacterial Respiration

This feed focuses on cellular respiration in bacteria, known as bacterial respiration. Discover the latest research here.