Lycopene from two food sources does not affect antioxidant or cholesterol status of middle-aged adults

Nutrition Journal
J K CollinsB A Clevidence

Abstract

Epidemiological studies have reported associations between reduced cardiovascular disease and diets rich in tomato and/or lycopene. Intervention studies have shown that lycopene-containing foods may reduce cholesterol levels and lipid peroxidation, factors implicated in the initiation of cardiovascular disease. The objective of this study was to determine whether consumption of lycopene rich foods conferred cardiovascular protection to middle-aged adults as indicated by plasma lipid concentrations and measures of ex vivo antioxidants. Ten healthy men and women consumed a low lycopene diet with no added lycopene (control treatment) or supplemented with watermelon or tomato juice each containing 20 mg lycopene. Subjects consumed each treatment for three weeks in a crossover design. Plasma, collected weekly was analyzed for total cholesterol, high density lipoprotein cholesterol (HDL-C) and triglyceride concentrations and for the antioxidant biomarkers of malondialdehyde formation products (MDA), plasma glutathione peroxidase (GPX) and ferric reducing ability of plasma (FRAP). Data were analyzed using Proc Mixed Procedure and associations between antioxidant and lipid measures were identified by Pearson's product moment correlatio...Continue Reading

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Citations

Nov 21, 2007·European Journal of Nutrition·Delphine GitenayEdmond Rock
Jul 10, 2007·The British Journal of Nutrition·Marja-Leena SilasteSohvi Hörkkö
May 13, 2010·Natural Product Research·Santosh K ShuklaSuman B Sharma
Sep 20, 2008·Journal of Medicinal Food·Hoda Salama IbrahimMaha Mohamed Essam El-din
Sep 12, 2012·Annals of Nutrition & Metabolism·P PalozzaA Cittadini
Nov 28, 2006·International Journal of Food Sciences and Nutrition·Carrie H S RuxtonDrew Walker
Jul 3, 2021·Nutrients·Ahmed IsmaeelPanagiotis Koutakis

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