Lycorine: a potential broad-spectrum agent against crop pathogenic fungi

Journal of Microbiology and Biotechnology
Jin-Wen ShenChun-Feng Zheng

Abstract

A screening test showed that lycorine exhibited significant antifungal activity against 24 pathogenic crop fungi at concentrations of 500 μg/ml and 100 μg/ml, respectively. Fusarium graminearum was selected for antifungal mechanism studies by observing its mycelial morphology and investigating the variations in its conductivity. In addition, the substance absorption and metabolism of F. graminearum were explored. The mechanism was revealed as being one by which lycorine destroyed the cellular membrane and further influenced substance absorption and cell metabolism.

Citations

Oct 24, 2014·BMC Complementary and Alternative Medicine·Francesca BonviciniGiovanna Angela Gentilomi
Oct 28, 2015·Plant Biotechnology Journal·Andrew Diamond, Isabel Desgagné-Penix
Feb 28, 2018·Phytotherapy Research : PTR·Jerald J Nair, Johannes van Staden
Apr 30, 2017·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Hui ZengJian Huang
Jun 12, 2020·Parasitology Research·Brenda Petró-SilveiraTiana Tasca

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An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

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