Lyme disease: clinical diagnosis and treatment

Canada Communicable Disease Report = Relevé Des Maladies Transmissibles Au Canada
T F HatchetteB L Johnston

Abstract

Lyme disease is an emerging zoonotic infection in Canada. As the Ixodes tick expands its range, more Canadians will be exposed to Borrelia burgdorferi, the bacterium that causes Lyme disease. To review the clinical diagnosis and treatment of Lyme disease for front-line clinicians. A literature search using PubMed and restricted to articles published in English between 1977 and 2014. Individuals in Lyme-endemic areas are at greatest risk, but not all tick bites transmit Lyme disease. The diagnosis is predominantly clinical. Patients with Lyme disease may present with early disease that is characterized by a "bull's eye rash", fever and myalgias or with early disseminated disease that can manifest with arthralgias, cardiac conduction abnormalities or neurologic symptoms. Late Lyme disease in North America typically manifests with oligoarticular arthritis but can present with a subacute encephalopathy. Antibiotic treatment is effective against Lyme disease and works best when given early in the infection. Prophylaxis with doxycyline may be indicated in certain circumstances. While a minority of patients may have persistent symptoms, evidence does not demonstrate that prolonged courses of antibiotics improve outcome. Clinicians nee...Continue Reading

Citations

Aug 21, 2020·BMJ : British Medical Journal·Mohammad S RazaiPippa Oakeshott
May 1, 2015·CJEM·Tahira Daya, Conor McKaigney
Oct 2, 2020·Biosensors·Connor Flynn, Anna Ignaszak
May 18, 2018·Canada Communicable Disease Report = Relevé Des Maladies Transmissibles Au Canada·S GasmiJ K Koffi
Nov 22, 2020·Tropical Medicine and Infectious Disease·Janet L H SperlingKatharine E Magor
Mar 11, 2021·Vector Borne and Zoonotic Diseases·Mariia ShkilnaArtem S Rogovskyy
Jun 21, 2020·Journal of Endodontics·Isabel MelloChris Lee

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Cardiac Conduction System

The cardiac conduction system is a specialized tract of myocardial cells responsible for maintaining normal cardiac rhythm. Discover the latest research on the cardiac conduction system here.

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Related Papers

Mayo Clinic Proceedings
Robert L BrattonFrederick D Edwards
Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society
J BerglöffB Feigl
© 2022 Meta ULC. All rights reserved