Abstract
Lymphatic drainage and circulation in periodontal tissues have been cited as important components of host defence and pathogenic mechanisms, but quantitative data are sparse because of the technical difficulties associated with small animal lymphatic studies. However, the lymphatic vessels draining the periodontal tissues and surrounding region are sufficiently large in sheep to permit surgical placement of lymphatic catheters. Consequently, lymph and recirculating lymphocytes can be continuously collected and this permits the quantitative assessment of local immune responses in these tissues. We have studied the lymphatic drainage pathways from the labial gingival tissues in sheep by two methods. First, in a series of anatomical studies (n = 6), a complex of Evan's blue dye and albumin was injected into the labial gingival tissues. One hour after injection the animals were sacrificed and the submandibular and cervical regions were dissected to expose the stained lymphatics. This anatomical study demonstrated 2 major drainage pathways: 1) cervical lymph ducts and; 2) efferent prescapular lymphatics. Secondly, to compare the relative importance of these two drainage pathways, radiolabeled protein (125I-albumin) was injected dire...Continue Reading
References
Oct 1, 1976·Laboratory Animals·D J Glover, J G Hall
Nov 1, 1976·Journal of Periodontology·T W Cutress
Sep 1, 1991·Journal of Periodontal Research·T AbeM Aono
Mar 1, 1991·Microvascular Research·L Bent-Hansen, J H Svendsen
May 1, 1989·Journal of Periodontology·M O IsmaielC Scully
Feb 1, 1967·The Australian Journal of Experimental Biology and Medical Science·G W Boyd
Jan 1, 1970·Journal of Periodontal Research·R R Ranney
Jun 1, 1971·Journal of Periodontology·L Shapiro, M P Ruben
Nov 1, 1968·Journal of Dental Research·B M Levy, S Bernick
Dec 1, 1971·Journal of Periodontology·M P RubenA A Bloom
Aug 1, 1984·The Anatomical Record·A A GeldofH L Langevoort
Apr 1, 1980·Journal of Comparative Pathology·J A SpenceP J Atkinson
Mar 1, 1994·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·A J YoungJ B Hay
Jan 1, 1959·Journal of Dental Research·L KRAINTZB R ELLIS
Jul 1, 1961·Quarterly Journal of Experimental Physiology and Cognate Medical Sciences·A K LASCELLES, B MORRIS
Sep 30, 1938·The Journal of Experimental Medicine·J M Yoffey, C K Drinker
Citations
Jun 8, 1999·The Anatomical Record·C MarchettiS Rizzo
Jun 26, 2009·Journal of Virology·Behzad HematiIsabelle Schwartz-Cornil
May 18, 1999·Seminars in Immunology·T SeabrookJ B Hay
Jan 26, 2002·Microscopy Research and Technique·Binh AuJohn B Hay
Jan 26, 2002·Microscopy Research and Technique·Yuushi MatsumotoSeiji Kato
Apr 20, 2020·European Journal of Oral Sciences·Anca VirtejEllen Berggreen
Feb 24, 2006·Journal of Veterinary Dentistry·Carsten StaszykAstrid Bienert
Aug 13, 2010·The Journal of Immunology : Official Journal of the American Association of Immunologists·Vanessa ContrerasIsabelle Schwartz-Cornil