Lymph node dissection and recurrent laryngeal nerve protection in minimally invasive esophagectomy

Annals of the New York Academy of Sciences
Zhen WangJie He

Abstract

Until now, neoadjuvant therapy plus surgical resection of the primary tumor and potential metastatic lymph nodes (LNs) has been the current optimal treatment for locally advanced thoracic esophageal cancer (EC). LN metastasis is one of the most negative prognostic factors for thoracic esophageal squamous cell carcinoma (ESCC). However, the extent of LN dissection for thoracic ESCC has long been controversial worldwide. LNs along the recurrent laryngeal nerve (RLN) were reported to have the highest frequency of metastases in thoracic ESCC, so lymphadenectomy along the bilateral RLN is necessary but quite challenging because of a high frequency of recurrent nerve palsy and related postoperative complications. With the development of minimally invasive devices and techniques in recent years, minimally invasive esophagectomy (MIE) has been widely applied in EC surgery. The topics of what the optimal extent of lymphadenectomy is and how the recurrent nerve should be well protected during MIE have been debated in recent years. The purpose of our review is specifically to address the patterns of LN metastasis, the extent of LN dissection, and the protection of the RLN in MIE for thoracic ESCC.

References

Sep 1, 1994·Annals of Surgery·H AkiyamaY Kajiyama
Sep 13, 2001·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·S Law, J Wong
Jun 28, 2003·The Journal of Thoracic and Cardiovascular Surgery·Kenshi KugeShiro Sasaguri
Jun 24, 2004·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·T NoguchiY Uchida
Aug 21, 2007·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·David P KelsenUNKNOWN USA Intergroup
Sep 23, 2009·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·William H AllumRuth E Langley
Dec 3, 2009·Annals of Surgical Oncology·Naveenraj SolomonLeonidas G Koniaris
Dec 25, 2009·Annals of Surgery·Nabil P RizkEugene H Blackstone
Apr 28, 2010·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Young Mog ShimKwhanmien Kim
Aug 11, 2010·World Journal of Gastroenterology : WJG·J Camilo Barreto, Mitchell C Posner
Nov 6, 2010·Interactive Cardiovascular and Thoracic Surgery·Hugh ColvinOmar A Khan
Jun 28, 2011·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·L PertlB Schneider-Stickler
Mar 8, 2012·Annals of Surgery·Natalie S BlencoweJane M Blazeby
Jun 1, 2012·The New England Journal of Medicine·P van HagenUNKNOWN CROSS Group
Aug 15, 2012·The Journal of Thoracic and Cardiovascular Surgery·Bin LiYang Zhang
Apr 30, 2013·Annals of Surgical Oncology·Ravi ShridharKenneth Meredith
Sep 24, 2013·The Annals of Thoracic Surgery·Ting YeHaiquan Chen
Mar 13, 2014·The Journal of Thoracic and Cardiovascular Surgery·Yuji TachimoriUNKNOWN Registration Committee for Esophageal Cancer of the Japan Esophageal Society
Jul 2, 2014·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Christophe MarietteJean-François Seitz
Oct 15, 2014·Interactive Cardiovascular and Thoracic Surgery·Yusuke TaniyamaNorikaki Ohuchi
Dec 10, 2014·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·H FujiwaraE Otsuji
Feb 27, 2015·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·S Y ParkH S Jung
Aug 21, 2015·Annals of Surgical Oncology·Yukiko NiwaYasuhiro Kodera
Sep 12, 2015·The Annals of Thoracic Surgery·Hitoshi FujiwaraEigo Otsuji
Oct 30, 2015·The British Journal of Surgery·W B RobbUNKNOWN French EsoGAstric Tumour working group - Fédération de Recherche En Chirurgie
Jan 12, 2016·Esophagus : Official Journal of the Japan Esophageal Society·Yuji TachimoriUNKNOWN Registration Committee for Esophageal Cancer of the Japan Esophageal Society
Jul 30, 2016·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·R van HillegersbergJ P Ruurda
Nov 5, 2016·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Thomas W RicePeter Goldstraw
Jan 24, 2017·Esophagus : Official Journal of the Japan Esophageal Society·UNKNOWN Japan Esophageal Society

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.