PMID: 8964151Aug 1, 1996Paper

Lymph node excision in thyroid carcinoma

Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen
H Dralle, O Gimm

Abstract

The prognostic value of lymph node metastases in thyroid cancer has been a matter of controversy for many years. However, during the past decade most multivariate analyses have shown a prognostic influence of lymph node metastases in papillary as well as medullary thyroid carcinoma constituting the basis for a standardized concept of lymphadenectomy oriented to the lymph node classification of the UICC (1993). Due to the frequency of lymph node metastases in the ipsilateral cervicocentral compartment (42-86%), in the ipsilateral cervicolateral compartment (32-68%), in the contralateral cervicolateral compartment (12-24%), and in the mediastinal compartment (3-20%), these compartments can be defined as the lymph node regions of the first, second, third and fourth order, respectively. Cervicocentral systematic lymphadenectomy should be part of the en bloc resection of the thyroid gland and the first lymph node region in any thyroid cancer. Cervicolateral as well as mediastinal lymphadenectomy should be performed according to the extent of lymph node involvement, i.e. systematically when multiple lymph node metastases are present, otherwise selectively. One exception is in medullary thyroid carcinoma, where a four-compartment lymp...Continue Reading

Citations

Mar 21, 1998·The British Journal of Surgery·O GimmH Dralle
Mar 2, 2005·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·H VogelsangJ R Siewert
Aug 16, 2008·Endocrine Journal·Yasuhiro Ito, Akira Miyauchi
Mar 9, 2010·Diagnostic Pathology·Xiaoqi LinJan F Silverman
Mar 5, 2013·Langenbeck's Archives of Surgery·Henning DralleUNKNOWN German Societies of General and Visceral Surgery; Endocrinology; Nuclear Medicine; Pathology; Radiooncology; Oncological Hem
Nov 11, 2009·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·H DralleA Machens
Oct 9, 2014·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·H Dralle, P Nguyen Thanh
Nov 27, 2007·Expert Opinion on Pharmacotherapy·Yasuhiro Ito, Akira Miyauchi
Jul 12, 2012·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·H Dralle
Sep 20, 2006·World Journal of Surgery·Yasuhiro ItoAkira Miyauchi
Feb 27, 2007·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·O Gimm, H Dralle
Dec 2, 2008·Best Practice & Research. Clinical Endocrinology & Metabolism·Henning Dralle, Andreas Machens

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