Lymph Node Metastasis in Colorectal Cancer

Surgical Oncology Clinics of North America
Ming Jin, Wendy L Frankel

Abstract

Pathologic examination of lymph nodes in patients with cancer remains crucial for postoperative treatment and prognosis prediction. In this article, the authors aim to review several important and challenging issues regarding lymph node metastasis in colorectal cancer using the AJCC staging manual, College of American Pathologists cancer protocol, as well as the literature. These topics include lymph node staging, the definition and controversies in tumor deposits, isolated tumor cells in lymph node and micrometastasis, lymph node ratio as a prognostic stratification factor, and neoadjuvant treatment effect in rectal cancer. Updates from the most recent AJCC 8th edition are included.

Citations

Apr 27, 2019·Cancer Science·Bing-Dong ZhangBao-Qing Jia
Aug 14, 2020·Journal of Surgical Oncology·Olivier BenoitJeremie H Lefevre
Nov 2, 2019·World Journal of Surgical Oncology·Shuiquan LinWuguang Lu
Aug 7, 2019·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Dipti M KaramchandaniDavid K Driman
Sep 19, 2020·OncoTargets and Therapy·Jie LiuMan Yi
Feb 11, 2021·BMC Gastroenterology·Tong-Hui XieHui Zhang
Oct 17, 2020·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·Hillary L SimonDeborah S Keller
Jul 6, 2020·Cancer Treatment Reviews·Pauline ParentAnthony Turpin
Oct 3, 2020·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·Edward AlabrabaStephen Fenwick
Aug 3, 2021·Technology in Cancer Research & Treatment·Lingxu HuangWeizhong Tang
Aug 22, 2021·International Journal of Colorectal Disease·Giorgio BianchiRenato Costi

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