PMID: 15346063Sep 4, 2004Paper

Lymph node metastasis in soft tissue sarcoma in an extremity

Clinical Orthopaedics and Related Research
Soha RiadJay S Wunder

Abstract

For patients with soft tissue sarcoma in an extremity, the outcome is thought to be poor if lymph node metastasis develops. The purpose of this study was to examine the impact of lymphatic involvement from soft tissue sarcoma on patient survival. Thirty-nine (3.7%) of 1066 patients who had surgery for soft tissue sarcoma in an extremity had lymph node metastases develop. Three (20%) of 15 patients with epithelioid sarcoma, four (19%) of 21 patients with rhabdomyosarcoma, two (11.1%) of 18 patients with clear cell sarcoma, and two (11.1%) of 18 patients with angiosarcoma had lymphatic involvement. Thirty patients who had resection of involved lymph nodes had an estimated 5-year survival of 57%, whereas nine patients treated without surgery all died within 30 months. An estimated 4-year survival of 71% for patients with isolated lymph node metastases was significantly better than 21% for patients with synchronous systemic and lymph node involvement. There was no difference in outcome for patients with isolated lymphatic involvement compared with patients with American Joint Committee on Cancer Stage III extremity sarcomas. These results suggest that long-term survival is possible after surgical resection of lymphatic metastases f...Continue Reading

References

Aug 1, 1992·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·J J GaynorM F Brennan
Oct 15, 1987·Cancer·J J Mazeron, H D Suit
Aug 1, 1983·Archives of Surgery·M P VezeridisC P Karakousis
Mar 1, 1996·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·J M CoindreG Contesso
May 1, 1996·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·P W PistersM F Brennan
Oct 6, 1997·Annals of Surgical Oncology·H M RossM F Brennan
Apr 14, 2000·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·C S TrovikA Wallöe
Jan 5, 2001·The Surgical Clinics of North America·J E GervasoniB Cady
Jul 19, 2002·Cancer·Darren J LittleRobert S Benjamin
May 2, 2003·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Neil H SegalAlan N Houghton

❮ Previous
Next ❯

Citations

Dec 15, 2005·Cancer·Michela CasanovaUNKNOWN Italian Soft Tissue Sarcoma Committee
Nov 13, 2008·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Emma RobinsonBrian O'Sullivan
Mar 5, 2009·Annals of Surgical Oncology·Ugwuji N MaduekweSam S Yoon
Aug 29, 2013·TheScientificWorldJournal·Lukas M NystromC Parker Gibbs
Dec 9, 2014·Journal of Surgical Oncology·Nader N MassarwehDaniel A Anaya
Nov 8, 2016·American Journal of Clinical Oncology·Chandra K KrishnanIlkyu Han
Jan 21, 2020·South Asian Journal of Cancer·Vineet KurisunkalBharat Rekhi
May 16, 2020·Journal of Surgical Oncology·Stéphane CollaudClemens Aigner
May 13, 2009·American Journal of Clinical Oncology·Joseph J KingChristian M Ogilvie
Jun 4, 2008·Annals of Surgical Oncology·G LahatR E Pollock
Jun 25, 2009·Annals of Surgical Oncology·G LahatD Lev
May 19, 2007·World Journal of Surgery·Can AtalayBesim Seref
Sep 1, 2007·Journal of Children's Orthopaedics·Michela CasanovaAndrea Ferrari
Apr 23, 2015·Iranian Journal of Radiology : a Quarterly Journal Published by the Iranian Radiological Society·Ryan Ka-Lok LeeAnthony Wing-Hung Chan
Sep 8, 2018·The Journal of the American Academy of Orthopaedic Surgeons·Christopher N JohnsonDarin Davidson
Aug 25, 2019·Skeletal Radiology·Jeffrey RosenthalAdam Daniel Singer
Mar 20, 2020·Molecular and Clinical Oncology·Kazuhiko HashimotoMasao Akagi
May 19, 2012·Journal of Surgical Oncology·Valerie A SmithEric J Lentsch
Nov 17, 2012·Annals of Plastic Surgery·Yu-Wen Tang, Chih-Sheng Lai
Jul 3, 2008·Langenbeck's Archives of Surgery·A DaigelerM Lehnhardt
Jun 27, 2014·Journal of Surgical Oncology·Jeffrey S KneislChandrajit P Raut
Jun 3, 2015·Journal of Surgical Oncology·Justin T HuntingtonRaphael E Pollock
Apr 27, 2016·Current Oncology Reports·Philip BlumenfeldDian Wang
Oct 4, 2014·SpringerPlus·Satoshi TsukushiNaoki Ishiguro
Sep 9, 2016·Clinical & Experimental Metastasis·Hiroshi UrakawaYoshihiro Nishida
Oct 28, 2016·Annals of Surgical Oncology·Brett L EckerGiorgos C Karakousis
Nov 28, 2018·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·M LehnhardtK Harati
Aug 19, 2020·Journal of Surgical Oncology·Matthew R ClaxtonMatthew T Houdek
May 12, 2009·World Journal of Surgery·Anja LachenmayerMatthias Peiper
Jun 10, 2014·Journal of Surgical Oncology·Karen L ShermanKarl Y Bilimoria
May 26, 2017·Diagnostic Cytopathology·Jahnavi GandhiDhaval Jetly
May 23, 2018·Skeletal Radiology·Nisreen S EzuddinTy K Subhawong
Aug 18, 2017·Upsala Journal of Medical Sciences·Hiroyuki TsuchieYoichi Shimada
Jan 10, 2020·International Journal of Surgical Oncology·Makoto EmoriToshihiko Yamashita
Dec 22, 2020·Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research·Dimitrios SchizasEmmanouil Pikoulis
Jan 5, 2021·Annals of Surgical Oncology·Nicholas M SiegelAdam S Levin
Jan 3, 2019·Clinical Orthopaedics and Related Research·Zachary MayoBenjamin J Miller

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.