Lymphatic mapping and sentinel lymph node biopsy in epidermoid carcinoma of the anal canal.

European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
S GretschelP M Schlag

Abstract

Although 15-25% of patients with anal cancer present with superficial inguinal lymph node metastases but the routine application of groin irradiation is controversial because of serious side effects. Inguinal sentinel lymph node biopsy (SLNB) can be used to select patients appropriately for inguinal radiation. The study evaluates the efficiency and clinical impact of SLNB. Forty patients with anal cancer underwent 1 ml Tc(99m)-Nanocolloid injection in four sites around the tumour. Patients with inguinal radio colloid enrichment were selected for sentinel lymph node biopsy (SLNB). Lymph node status was examined by haematoxylin and eosin (H&E) as well as immunohistochemistry-staining. All SLN-positive patients were scheduled for inguinal radiation; SLN-negative patients with T1 and early T2 tumours were not scheduled for inguinal radiation. SLN were detected in 36/40 patients. Three common patterns of lymphatic drainage were observed: mesenterial, iliacal and inguinal. Twenty patients with inguinal SLN underwent SLN-biopsy. 6/20 patients were SLN-positive. In 10/20 patients SLNB altered the therapy plan--four patients with T1-tumours and positive SLN had additional groin irradiation, whereas 6 patients with small T2-tumors and tu...Continue Reading

References

Mar 11, 1976·American Journal of Surgery·G T Golden, J S Horsley
Nov 1, 1988·International Journal of Radiation Oncology, Biology, Physics·S W DoggettS T Cantril
May 1, 1974·Diseases of the Colon and Rectum·N D NigroB Considine
Apr 1, 1968·The British Journal of Surgery·H R Wolfe, H J Bussey
Jan 1, 1984·American Journal of Surgery·R J SalmonJ Rousseau
Nov 1, 1982·Diseases of the Colon and Rectum·B J CummingsW D Rider
Apr 1, 1994·The British Journal of Surgery·G T DeansR A Spence
Mar 16, 2000·The New England Journal of Medicine·D P RyanR J Mayer
Jul 13, 2002·Journal of Surgical Oncology·Frederick L Greene, Leslie H Sobin
Sep 25, 2002·ANZ Journal of Surgery·Philippa RabbittNicholas Rieger
Mar 17, 2004·Annals of Surgical Oncology·Christoph UlmerPeter Michael Schlag
Nov 1, 1936·Annals of Surgery·J P Nesselrod

❮ Previous
Next ❯

Citations

Apr 29, 2010·Techniques in Coloproctology·D C DaminL M Kliemann
May 4, 2010·Clinics in Colon and Rectal Surgery·Jennifer Blumetti, Amir L Bastawrous
Nov 17, 2009·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·T HamanoY Kobayashi
Jan 29, 2009·World Journal of Surgical Oncology·Stephen P PovoskiEdward W Martin
Aug 19, 2010·Annals of Surgical Oncology·Massimiliano MistrangeloEnrica Milanesi
Dec 1, 2012·World Journal of Gastroenterology : WJG·Paola De NardiCarlo Staudacher
Aug 31, 2010·Annals of Surgical Oncology·Paola De NardiCarlo Staudacher
May 17, 2011·International Journal of Radiation Oncology, Biology, Physics·Cécile OrtholanDidier Cowen
Jul 28, 2009·International Journal of Radiation Oncology, Biology, Physics·Massimiliano MistrangeloAntonio Mussa
Mar 7, 2009·Gastroentérologie Clinique Et Biologique·M Mistrangelo, M Morino
Jul 23, 2013·International Journal of Surgery·A NooraniR J Davies
Dec 3, 2014·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·S KadkhodayanR Sadeghi
May 12, 2019·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·P De NardiR Rosati
Jan 31, 2016·Clinical Nuclear Medicine·Georgios GemenetzisPantelis Vassiliu

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Squamous Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.

Related Papers

European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
D C DaminG Schwartsmann
Gastroentérologie Clinique Et Biologique
Massimiliano Mistrangelo, Mario Morino
© 2021 Meta ULC. All rights reserved